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<language>en-us</language>
<description>Sciences Indexed Since 1998</description>
<title>Toxicology - Sciences Indexed Since 1998</title>
<atom:link href="http://scienceindex.com/xmlfeeds.php?cmd=popular&amp;id=34" rel="self" type="application/rss+xml" /><link>http://scienceindex.com/view/34/Toxicology/1.html</link>
<item>
<title>An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants</title>
<link>http://scienceindex.com/stories/3128958/An_automated_Fpgbased_FADU_method_for_the_detection_of_oxidative_DNA_lesions_and_screening_of_antioxidants.html</link>
<guid>http://scienceindex.com/stories/3128958/An_automated_Fpgbased_FADU_method_for_the_detection_of_oxidative_DNA_lesions_and_screening_of_antioxidants.html</guid><description><![CDATA[The oxidation of guanine to 8-oxo-2’-deoxyguanosine (8-oxo-dG) is one of the most abundant and best studied oxidative DNA lesions and is commonly used as a biomarker for oxidative stress. Over th...]]></description>
<pubDate>Wed, 22 May 2013 02:07:01 +0100</pubDate>
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<title>Assuring safety without animal testing: The case for the human testis in vitro</title>
<link>http://scienceindex.com/stories/3128544/Assuring_safety_without_animal_testing_The_case_for_the_human_testis_in_vitro.html</link>
<guid>http://scienceindex.com/stories/3128544/Assuring_safety_without_animal_testing_The_case_for_the_human_testis_in_vitro.html</guid><description><![CDATA[From 15 to 17 June 2011, a dedicated workshop was held on the subject of in vitro models for mammalian spermatogenesis and their applications in toxicological hazard and risk assessment. The worksh...]]></description>
<pubDate>Tue, 21 May 2013 23:22:03 +0100</pubDate>
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<title>Sialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins</title>
<link>http://scienceindex.com/stories/3128038/Sialorrhea_Anatomy_Pathophysiology_and_Treatment_with_Emphasis_on_the_Role_of_Botulinum_Toxins.html</link>
<guid>http://scienceindex.com/stories/3128038/Sialorrhea_Anatomy_Pathophysiology_and_Treatment_with_Emphasis_on_the_Role_of_Botulinum_Toxins.html</guid><description><![CDATA[Sialorrhea or excessive drooling is a major issue in children with cerebral palsy and adults with neurodegenerative disorders. In this review, we describe the clinical features, anatomy and physiol...]]></description>
<pubDate>Tue, 21 May 2013 19:01:03 +0100</pubDate>
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<item>
<title>Estimated Dietary Exposure to Mycotoxins after Taking into Account the Cooking of Staple Foods in Japan</title>
<link>http://scienceindex.com/stories/3128037/Estimated_Dietary_Exposure_to_Mycotoxins_after_Taking_into_Account_the_Cooking_of_Staple_Foods_in_Japan.html</link>
<guid>http://scienceindex.com/stories/3128037/Estimated_Dietary_Exposure_to_Mycotoxins_after_Taking_into_Account_the_Cooking_of_Staple_Foods_in_Japan.html</guid><description><![CDATA[Mycotoxins are commonly present in cereal grains and are not completely destroyed during their cooking and processing. When mycotoxins contaminate staple foods, the risk for exposure becomes seriou...]]></description>
<pubDate>Tue, 21 May 2013 19:01:03 +0100</pubDate>
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<item>
<title>Venomous Secretions from Marine Snails of the Terebridae Family Target Acetylcholine Receptors</title>
<link>http://scienceindex.com/stories/3128036/Venomous_Secretions_from_Marine_Snails_of_the_Terebridae_Family_Target_Acetylcholine_Receptors.html</link>
<guid>http://scienceindex.com/stories/3128036/Venomous_Secretions_from_Marine_Snails_of_the_Terebridae_Family_Target_Acetylcholine_Receptors.html</guid><description><![CDATA[Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies at...]]></description>
<pubDate>Tue, 21 May 2013 19:01:03 +0100</pubDate>
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<item>
<title>A comparative survey of chemistry-driven in silico methods to identify hazardous substances under REACH</title>
<link>http://scienceindex.com/stories/3127972/A_comparative_survey_of_chemistrydriven_in_silico_methods_to_identify_hazardous_substances_under_REACH.html</link>
<guid>http://scienceindex.com/stories/3127972/A_comparative_survey_of_chemistrydriven_in_silico_methods_to_identify_hazardous_substances_under_REACH.html</guid><description><![CDATA[This paper presents an inventory of in silico screening tools to identify substance properties of concern under the European chemicals’ legislation REACH. The objective is to support the selectio...]]></description>
<pubDate>Tue, 21 May 2013 18:12:25 +0100</pubDate>
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<item>
<title>AhV_aPA-induced vasoconstriction involves the IP3Rs-mediated Ca2+ releasing</title>
<link>http://scienceindex.com/stories/3127760/AhV_aPAinduced_vasoconstriction_involves_the_IP3Rsmediated_Ca2_releasing.html</link>
<guid>http://scienceindex.com/stories/3127760/AhV_aPAinduced_vasoconstriction_involves_the_IP3Rsmediated_Ca2_releasing.html</guid><description><![CDATA[AhV_aPA, the acidic PLA2 purified from Agkistrodon halys pallas venom, was previously reported to possess a strong enzymatic activity and can remarkably induce a further contractile response on the...]]></description>
<pubDate>Tue, 21 May 2013 16:09:47 +0100</pubDate>
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<title>The ecotoxicological evaluation of Cylindrospermopsis raciborskii from Lake Balaton (Hungary) employing a battery of bioassays and chemical screening</title>
<link>http://scienceindex.com/stories/3127759/The_ecotoxicological_evaluation_of_Cylindrospermopsis_raciborskii_from_Lake_Balaton_Hungary_employing_a_battery_of_bioassays_and_chemical_screening.html</link>
<guid>http://scienceindex.com/stories/3127759/The_ecotoxicological_evaluation_of_Cylindrospermopsis_raciborskii_from_Lake_Balaton_Hungary_employing_a_battery_of_bioassays_and_chemical_screening.html</guid><description><![CDATA[Ecotoxicity of four Cylindrospermopsis raciborskii strains (ACT 9502, ACT 9503, ACT 9504, ACT 9505) isolated from Lake Balaton (Hungary) was evaluated in four aquatic bioassays including the Thamno...]]></description>
<pubDate>Tue, 21 May 2013 16:09:47 +0100</pubDate>
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<title>Biochemical and immunological characteristics of Peruvian Loxosceles laeta spider venom: Neutralization of its toxic effects by anti-loxoscelic antivenoms</title>
<link>http://scienceindex.com/stories/3127758/Biochemical_and_immunological_characteristics_of_Peruvian_Loxosceles_laeta_spider_venom_Neutralization_of_its_toxic_effects_by_antiloxoscelic_antivenoms.html</link>
<guid>http://scienceindex.com/stories/3127758/Biochemical_and_immunological_characteristics_of_Peruvian_Loxosceles_laeta_spider_venom_Neutralization_of_its_toxic_effects_by_antiloxoscelic_antivenoms.html</guid><description><![CDATA[This manuscript describes the general biochemical properties and immunological characteristics of Peruvian spider Loxosceles laeta venom (PLlv), which is responsible for the largest number of accid...]]></description>
<pubDate>Tue, 21 May 2013 16:09:47 +0100</pubDate>
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<item>
<title>Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation</title>
<link>http://scienceindex.com/stories/3127654/Resveratrol_ameliorates_methotrexateinduced_hepatotoxicity_in_rats_via_inhibition_of_lipid_peroxidation.html</link>
<guid>http://scienceindex.com/stories/3127654/Resveratrol_ameliorates_methotrexateinduced_hepatotoxicity_in_rats_via_inhibition_of_lipid_peroxidation.html</guid><description><![CDATA[Hepatotoxicity is one of the major complications of methotrexate (MTX) therapy. This study was carried out to evaluate the possible protective effect of resveratrol (trans-3,5,4'-trihydroxystilbene...]]></description>
<pubDate>Tue, 21 May 2013 15:12:12 +0100</pubDate>
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<title>N-Acetylcysteine prevents doxorubucine-induced cardiotoxicity in rats</title>
<link>http://scienceindex.com/stories/3127653/NAcetylcysteine_prevents_doxorubucineinduced_cardiotoxicity_in_rats.html</link>
<guid>http://scienceindex.com/stories/3127653/NAcetylcysteine_prevents_doxorubucineinduced_cardiotoxicity_in_rats.html</guid><description><![CDATA[This study is designed to observe the effects of N-acetylcysteine (NAC) on doxorubucine-induced cardiac toxicity in rats both histologically and biochemically. Totally 32 rats divided equally into ...]]></description>
<pubDate>Tue, 21 May 2013 15:12:12 +0100</pubDate>
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<title>Apoptotic cell death in rat epididymis following epichlorohydrin treatment</title>
<link>http://scienceindex.com/stories/3127652/Apoptotic_cell_death_in_rat_epididymis_following_epichlorohydrin_treatment.html</link>
<guid>http://scienceindex.com/stories/3127652/Apoptotic_cell_death_in_rat_epididymis_following_epichlorohydrin_treatment.html</guid><description><![CDATA[Epichlorohydrin (ECH) is an antifertility agent that acts both as an epididymal toxicant and an agent capable of directly affecting sperm motility. This study identified the time course of apoptoti...]]></description>
<pubDate>Tue, 21 May 2013 15:12:12 +0100</pubDate>
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<title>Effect of escitalopram on cardiomyopathy-induced anxiety in mice</title>
<link>http://scienceindex.com/stories/3127651/Effect_of_escitalopram_on_cardiomyopathyinduced_anxiety_in_mice.html</link>
<guid>http://scienceindex.com/stories/3127651/Effect_of_escitalopram_on_cardiomyopathyinduced_anxiety_in_mice.html</guid><description><![CDATA[The present study was aimed to evaluate the effect of escitalopram on anxiety following doxorubicin (DOX)-induced cardiomyopathy, a rodent model for heart failure (HF), in mice. The study was carri...]]></description>
<pubDate>Tue, 21 May 2013 15:12:12 +0100</pubDate>
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<title>Addressing bioterrorism concerns: Options for investigating the mechanism of action of Staphylococcus aureus enterotoxin B</title>
<link>http://scienceindex.com/stories/3127650/Addressing_bioterrorism_concerns_Options_for_investigating_the_mechanism_of_action_of_Staphylococcus_aureus_enterotoxin_B.html</link>
<guid>http://scienceindex.com/stories/3127650/Addressing_bioterrorism_concerns_Options_for_investigating_the_mechanism_of_action_of_Staphylococcus_aureus_enterotoxin_B.html</guid><description><![CDATA[Staphylococcal enterotoxin B (SEB) is of concern to military and civilian populations as a bioterrorism threat agent. It is a highly potent toxin produced by Staphylococcus aureus and is stable in ...]]></description>
<pubDate>Tue, 21 May 2013 15:12:11 +0100</pubDate>
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<title>Aryl hydrocarbon receptor negatively regulates expression of the plakoglobin gene (Jup)</title>
<link>http://scienceindex.com/stories/3127080/Aryl_hydrocarbon_receptor_negatively_regulates_expression_of_the_plakoglobin_gene_Jup.html</link>
<guid>http://scienceindex.com/stories/3127080/Aryl_hydrocarbon_receptor_negatively_regulates_expression_of_the_plakoglobin_gene_Jup.html</guid><description><![CDATA[Plakoglobin (PG) is an important component of intercellular junctions, including both desmosomes and adherens junctions, which is known as a tumor suppressor. Although mutations in the plakoglobin ...]]></description>
<pubDate>Tue, 21 May 2013 10:27:42 +0100</pubDate>
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<title>Comparison of electrophysiological data from human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) to functional pre-clinical safety assays</title>
<link>http://scienceindex.com/stories/3127079/Comparison_of_electrophysiological_data_from_human_induced_pluripotent_stem_cell_derived_cardiomyocytes_hiPSCCMs_to_functional_preclinical_safety_assays.html</link>
<guid>http://scienceindex.com/stories/3127079/Comparison_of_electrophysiological_data_from_human_induced_pluripotent_stem_cell_derived_cardiomyocytes_hiPSCCMs_to_functional_preclinical_safety_assays.html</guid><description><![CDATA[Human induced pluripotent stem cell cardiomyocytes (hiPSC-CMs) are a potential source to develop assays for predictive electrophysiological safety screening. Published studies show that the relevan...]]></description>
<pubDate>Tue, 21 May 2013 10:27:42 +0100</pubDate>
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<title>Modulating effects of hesperidin on key carbohydrate-metabolizing enzymes, lipid profile, and membrane-bound adenosine triphosphatases against 7,12-dimethylbenz(a)anthracene-induced breast carcinogenesis</title>
<link>http://scienceindex.com/stories/3126866/Modulating_effects_of_hesperidin_on_key_carbohydratemetabolizing_enzymes_lipid_profile_and_membranebound_adenosine_triphosphatases_against_712dimethylbenzaanthraceneinduced_breast_carcinogenesis.html</link>
<guid>http://scienceindex.com/stories/3126866/Modulating_effects_of_hesperidin_on_key_carbohydratemetabolizing_enzymes_lipid_profile_and_membranebound_adenosine_triphosphatases_against_712dimethylbenzaanthraceneinduced_breast_carcinogenesis.html</guid><description><![CDATA[The aim of this study was to document the effect of hesperidin on the key enzyme activities of carbohydrate metabolism, lipid profile, and membrane-bound adenosine triphosphatases (ATPases) during ...]]></description>
<pubDate>Tue, 21 May 2013 08:30:21 +0100</pubDate>
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<title>Inhalation toxicity of 316L stainless steel powder in relation to bioaccessibility</title>
<link>http://scienceindex.com/stories/3126867/Inhalation_toxicity_of_316L_stainless_steel_powder_in_relation_to_bioaccessibility.html</link>
<guid>http://scienceindex.com/stories/3126867/Inhalation_toxicity_of_316L_stainless_steel_powder_in_relation_to_bioaccessibility.html</guid><description><![CDATA[The Globally Harmonized System for Classification and Labelling of Chemicals (GHS) considers metallic alloys, such as nickel (Ni)-containing stainless steel (SS), as mixtures of substances, without...]]></description>
<pubDate>Tue, 21 May 2013 08:30:21 +0100</pubDate>
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<title>Withdrawal syndrome caused by naltrexone in opioid abusers</title>
<link>http://scienceindex.com/stories/3126868/Withdrawal_syndrome_caused_by_naltrexone_in_opioid_abusers.html</link>
<guid>http://scienceindex.com/stories/3126868/Withdrawal_syndrome_caused_by_naltrexone_in_opioid_abusers.html</guid><description><![CDATA[Naltrexone is a competitive opioid receptor antagonist acting at the &amp;micro;- and k-opioid receptors that blocks the euphoric effects of exogenous administered opioids. When used in opioid-dependen...]]></description>
<pubDate>Tue, 21 May 2013 08:30:21 +0100</pubDate>
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<title>Assessment of an in vitro transport model using BeWo b30 cells to predict placental transfer of compounds</title>
<link>http://scienceindex.com/stories/3126526/Assessment_of_an_in_vitro_transport_model_using_BeWo_b30_cells_to_predict_placental_transfer_of_compounds.html</link>
<guid>http://scienceindex.com/stories/3126526/Assessment_of_an_in_vitro_transport_model_using_BeWo_b30_cells_to_predict_placental_transfer_of_compounds.html</guid><description><![CDATA[The human ex vivo placental perfusion model has regularly been used to study the transplacental transport of compounds. However, this method is laborious and dependent on the presence of fresh huma...]]></description>
<pubDate>Tue, 21 May 2013 05:11:50 +0100</pubDate>
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<title>The effect of perinatal lead exposure on dopamine receptor d2 expression in morphine dependent rats</title>
<link>http://scienceindex.com/stories/3125503/The_effect_of_perinatal_lead_exposure_on_dopamine_receptor_d2_expression_in_morphine_dependent_rats.html</link>
<guid>http://scienceindex.com/stories/3125503/The_effect_of_perinatal_lead_exposure_on_dopamine_receptor_d2_expression_in_morphine_dependent_rats.html</guid><description><![CDATA[The aim of this study was to investigate the behavioral and molecular effects of pre- and postnatal lead (Pb) exposure on the expression of morphine withdrawal and tolerance in adult rats. Rats wer...]]></description>
<pubDate>Mon, 20 May 2013 22:53:52 +0100</pubDate>
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<title>Neurotoxic effects induced by endosulfan exposure during pregnancy and lactation in female and male rat striatum</title>
<link>http://scienceindex.com/stories/3125502/Neurotoxic_effects_induced_by_endosulfan_exposure_during_pregnancy_and_lactation_in_female_and_male_rat_striatum.html</link>
<guid>http://scienceindex.com/stories/3125502/Neurotoxic_effects_induced_by_endosulfan_exposure_during_pregnancy_and_lactation_in_female_and_male_rat_striatum.html</guid><description><![CDATA[Possible neurotoxic effects induced by endosulfan exposure during pregnancy and lactation in striatum of Sprague-Dawley female and male offspring rats have been evaluated. Dams were treated orally ...]]></description>
<pubDate>Mon, 20 May 2013 22:53:51 +0100</pubDate>
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<title>Uroprotective Effect of Pentoxifylline in Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats</title>
<link>http://scienceindex.com/stories/3125144/Uroprotective_Effect_of_Pentoxifylline_in_CyclophosphamideInduced_Hemorrhagic_Cystitis_in_Rats.html</link>
<guid>http://scienceindex.com/stories/3125144/Uroprotective_Effect_of_Pentoxifylline_in_CyclophosphamideInduced_Hemorrhagic_Cystitis_in_Rats.html</guid><description><![CDATA[The role of phosphodiesterase inhibitor, pentoxifylline, in the prevention of cyclophosphamide-induced hemorrhagic cystitis was evaluated in a rat model. Hemorrhagic cystitis was induced in rats by...]]></description>
<pubDate>Mon, 20 May 2013 19:53:46 +0100</pubDate>
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<title>A Norwegian Study of the Suitability of Hair Samples in Epidemiological Research of Alcohol, Nicotine and Drug Use</title>
<link>http://scienceindex.com/stories/3124559/A_Norwegian_Study_of_the_Suitability_of_Hair_Samples_in_Epidemiological_Research_of_Alcohol_Nicotine_and_Drug_Use.html</link>
<guid>http://scienceindex.com/stories/3124559/A_Norwegian_Study_of_the_Suitability_of_Hair_Samples_in_Epidemiological_Research_of_Alcohol_Nicotine_and_Drug_Use.html</guid><description><![CDATA[A feasibility study was performed to examine the effectiveness of hair testing in determining the prevalence of drug use in a young adult population. The study included 200 randomly selected young ...]]></description>
<pubDate>Mon, 20 May 2013 13:43:12 +0100</pubDate>
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<title>Inhibition of cytochrome P450s enhances (+)-usnic acid cytotoxicity in primary cultured rat hepatocytes</title>
<link>http://scienceindex.com/stories/3124558/Inhibition_of_cytochrome_P450s_enhances_usnic_acid_cytotoxicity_in_primary_cultured_rat_hepatocytes.html</link>
<guid>http://scienceindex.com/stories/3124558/Inhibition_of_cytochrome_P450s_enhances_usnic_acid_cytotoxicity_in_primary_cultured_rat_hepatocytes.html</guid><description><![CDATA[(+)-Usnic acid (UA) is consumed as a dietary supplement to promote weight loss; however, dietary supplements containing UA have been associated with clinical cases of severe liver injury. UA has be...]]></description>
<pubDate>Mon, 20 May 2013 13:41:21 +0100</pubDate>
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<title>Ketamine attenuates cytochrome p450 aromatase gene expression and estradiol-17β levels in zebrafish early life stages</title>
<link>http://scienceindex.com/stories/3124557/Ketamine_attenuates_cytochrome_p450_aromatase_gene_expression_and_estradiol17_levels_in_zebrafish_early_life_stages.html</link>
<guid>http://scienceindex.com/stories/3124557/Ketamine_attenuates_cytochrome_p450_aromatase_gene_expression_and_estradiol17_levels_in_zebrafish_early_life_stages.html</guid><description><![CDATA[Ketamine, a dissociative anesthetic, is a noncompetitive antagonist of N-methyl-D-aspartate-type glutamate receptors. In rodents and non-human primates as well as in zebrafish embryos, ketamine has...]]></description>
<pubDate>Mon, 20 May 2013 13:41:21 +0100</pubDate>
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<title>Developmental Exposure to As, Cd, and Pb Mixture Diminishes Skeletal Growth and Causes Osteopenia at Maturity via Osteoblast and Chondrocyte Malfunctioning in Female Rats</title>
<link>http://scienceindex.com/stories/3123650/Developmental_Exposure_to_As_Cd_and_Pb_Mixture_Diminishes_Skeletal_Growth_and_Causes_Osteopenia_at_Maturity_via_Osteoblast_and_Chondrocyte_Malfunctioning_in_Female_Rats.html</link>
<guid>http://scienceindex.com/stories/3123650/Developmental_Exposure_to_As_Cd_and_Pb_Mixture_Diminishes_Skeletal_Growth_and_Causes_Osteopenia_at_Maturity_via_Osteoblast_and_Chondrocyte_Malfunctioning_in_Female_Rats.html</guid><description><![CDATA[We studied the effect of metal mixture (MM), comprising As, Cd, and Pb, in developing female rat skeleton from gestation day 5 until postnatal day 60 (P-60). MM resulted in synergistic inhibition i...]]></description>
<pubDate>Sun, 19 May 2013 07:43:12 +0100</pubDate>
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<title>Paraquat Poisonings in France during the European Ban: Experience of the Poison Control Center in Marseille</title>
<link>http://scienceindex.com/stories/3123511/Paraquat_Poisonings_in_France_during_the_European_Ban_Experience_of_the_Poison_Control_Center_in_Marseille.html</link>
<guid>http://scienceindex.com/stories/3123511/Paraquat_Poisonings_in_France_during_the_European_Ban_Experience_of_the_Poison_Control_Center_in_Marseille.html</guid><description><![CDATA[Paraquat, a widely used herbicide in the world, has caused severe and fatal poisonings. Because of its high toxicity, the European Union withdrew paraquat from its market in July 2007. The purpose ...]]></description>
<pubDate>Sun, 19 May 2013 04:26:48 +0100</pubDate>
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<title>Reversal of Thienopyridine-Induced Platelet Dysfunction Following Desmopressin Administration</title>
<link>http://scienceindex.com/stories/3123510/Reversal_of_ThienopyridineInduced_Platelet_Dysfunction_Following_Desmopressin_Administration.html</link>
<guid>http://scienceindex.com/stories/3123510/Reversal_of_ThienopyridineInduced_Platelet_Dysfunction_Following_Desmopressin_Administration.html</guid><description><![CDATA[Adenosine diphosphate (ADP)-receptor antagonists are widely used for thrombus prevention, although reversing their platelet dysfunction is difficult. This study evaluated the ability of desmopressi...]]></description>
<pubDate>Sun, 19 May 2013 04:26:47 +0100</pubDate>
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<title>Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells</title>
<link>http://scienceindex.com/stories/3123344/Individual_and_combined_effects_of_Fusarium_toxins_on_the_mRNA_expression_of_proinflammatory_cytokines_in_swine_jejunal_epithelial_cells.html</link>
<guid>http://scienceindex.com/stories/3123344/Individual_and_combined_effects_of_Fusarium_toxins_on_the_mRNA_expression_of_proinflammatory_cytokines_in_swine_jejunal_epithelial_cells.html</guid><description><![CDATA[Fusarium toxins have been arousing public interest in recent years because of their potential health hazards for humans and agricultural livestock. It was hypothesized that selected pro-inflammator...]]></description>
<pubDate>Sun, 19 May 2013 00:24:36 +0100</pubDate>
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<title>Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway</title>
<link>http://scienceindex.com/stories/3123343/Naringin_inhibits_growth_potential_of_human_triplenegative_breast_cancer_cells_by_targeting_catenin_signaling_pathway.html</link>
<guid>http://scienceindex.com/stories/3123343/Naringin_inhibits_growth_potential_of_human_triplenegative_breast_cancer_cells_by_targeting_catenin_signaling_pathway.html</guid><description><![CDATA[Triple-negative (ER-/PR-/HER2-) breast cancer (TNBC) is a severe clinical problem because of its relatively poorer prognosis, aggressive behaviour and lack of targeted therapies. Naringin, a major ...]]></description>
<pubDate>Sun, 19 May 2013 00:24:36 +0100</pubDate>
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<title>Endogenous A1 Adenosine Receptor Protects Mice from Acute Ethanol-Induced Hepatotoxicity</title>
<link>http://scienceindex.com/stories/3123174/Endogenous_A1_Adenosine_Receptor_Protects_Mice_from_Acute_EthanolInduced_Hepatotoxicity.html</link>
<guid>http://scienceindex.com/stories/3123174/Endogenous_A1_Adenosine_Receptor_Protects_Mice_from_Acute_EthanolInduced_Hepatotoxicity.html</guid><description><![CDATA[Previous studies have indicated a critical role of adenosine and its receptors in the pathogenesis of liver diseases. The aim of this study was to determine the contribution of A1 adenosine recepto...]]></description>
<pubDate>Sat, 18 May 2013 21:05:35 +0100</pubDate>
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<title>The effects of 8-OH-DPAT on neuroinflammation after sarin exposure in mice</title>
<link>http://scienceindex.com/stories/3123173/The_effects_of_8OHDPAT_on_neuroinflammation_after_sarin_exposure_in_mice.html</link>
<guid>http://scienceindex.com/stories/3123173/The_effects_of_8OHDPAT_on_neuroinflammation_after_sarin_exposure_in_mice.html</guid><description><![CDATA[Poisoning by organophosphate nerve agents can induce seizures which rapidly become refractory to treatment and result in brain damage. Current therapies have only a narrow time frame for effective ...]]></description>
<pubDate>Sat, 18 May 2013 21:05:35 +0100</pubDate>
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<title>Disposition and Excretion of 14C-AHTN (7-Acetyl-1,1,3,4,4,6-Hexamethyl-1,2,3,4-Tetrahydronaphthalene) and 14C-HHCB (1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethyl-Cyclopenta-Gamma-2-Benzopyran) After Intravenous Administration to Sprague-Dawley Rats and Dom</title>
<link>http://scienceindex.com/stories/3122934/Disposition_and_Excretion_of_14CAHTN_7Acetyl113446Hexamethyl1234Tetrahydronaphthalene_and_14CHHCB_134678Hexahydro466788HexamethylCyclopentaGamma2Benzopyran_After_Intravenous_Administration_to_SpragueDawley_Rats_and_Dom.html</link>
<guid>http://scienceindex.com/stories/3122934/Disposition_and_Excretion_of_14CAHTN_7Acetyl113446Hexamethyl1234Tetrahydronaphthalene_and_14CHHCB_134678Hexahydro466788HexamethylCyclopentaGamma2Benzopyran_After_Intravenous_Administration_to_SpragueDawley_Rats_and_Dom.html</guid><description><![CDATA[7-Acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene (AHTN ) and 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-gamma-2-benzopyran (HHCB) are polycyclic musks widely used as fragra...]]></description>
<pubDate>Sat, 18 May 2013 18:00:19 +0100</pubDate>
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<title>The essential comet assay: a comprehensive guide to measuring DNA damage and repair</title>
<link>http://scienceindex.com/stories/3122701/The_essential_comet_assay_a_comprehensive_guide_to_measuring_DNA_damage_and_repair.html</link>
<guid>http://scienceindex.com/stories/3122701/The_essential_comet_assay_a_comprehensive_guide_to_measuring_DNA_damage_and_repair.html</guid><description><![CDATA[The comet assay (single cell gel electrophoresis) is the most common method for measuring DNA damage in eukaryotic cells or disaggregated tissues. The assay depends on the relaxation of supercoiled...]]></description>
<pubDate>Sat, 18 May 2013 14:34:07 +0100</pubDate>
</item>
<item>
<title>Effect of caffeic acid on Ca2+ homeostasis and apoptosis in SCM1 human gastric cancer cells</title>
<link>http://scienceindex.com/stories/3122700/Effect_of_caffeic_acid_on_Ca2_homeostasis_and_apoptosis_in_SCM1_human_gastric_cancer_cells.html</link>
<guid>http://scienceindex.com/stories/3122700/Effect_of_caffeic_acid_on_Ca2_homeostasis_and_apoptosis_in_SCM1_human_gastric_cancer_cells.html</guid><description><![CDATA[Caffeic acid is a natural phenolic compound that affects cellular Ca2+ homeostasis and viability in different cells. This study examined the effect of caffeic acid on cytosolic free Ca2+ concentrat...]]></description>
<pubDate>Sat, 18 May 2013 14:34:07 +0100</pubDate>
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<item>
<title>Study of Charge-Dependent Transport and Toxicity of Peptide-Functionalized Silver Nanoparticles Using Zebrafish Embryos and Single Nanoparticle Plasmonic Spectroscopy</title>
<link>http://scienceindex.com/stories/3121783/Study_of_ChargeDependent_Transport_and_Toxicity_of_PeptideFunctionalized_Silver_Nanoparticles_Using_Zebrafish_Embryos_and_Single_Nanoparticle_Plasmonic_Spectroscopy.html</link>
<guid>http://scienceindex.com/stories/3121783/Study_of_ChargeDependent_Transport_and_Toxicity_of_PeptideFunctionalized_Silver_Nanoparticles_Using_Zebrafish_Embryos_and_Single_Nanoparticle_Plasmonic_Spectroscopy.html</guid><description><![CDATA[Nanomaterials possess unusually high surface area-to-volume ratios and surface-determined physicochemical properties. It is essential to understand their surface-dependent toxicity in order to rati...]]></description>
<pubDate>Sat, 18 May 2013 06:41:45 +0100</pubDate>
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<title>Potentially mutagenic impurities: Analysis of structural classes and carcinogenic potencies of chemical intermediates in pharmaceutical syntheses supports alternative methods to the default TTC for calculating safe levels of impurities</title>
<link>http://scienceindex.com/stories/3121315/Potentially_mutagenic_impurities_Analysis_of_structural_classes_and_carcinogenic_potencies_of_chemical_intermediates_in_pharmaceutical_syntheses_supports_alternative_methods_to_the_default_TTC_for_calculating_safe_levels_of_impurities.html</link>
<guid>http://scienceindex.com/stories/3121315/Potentially_mutagenic_impurities_Analysis_of_structural_classes_and_carcinogenic_potencies_of_chemical_intermediates_in_pharmaceutical_syntheses_supports_alternative_methods_to_the_default_TTC_for_calculating_safe_levels_of_impurities.html</guid><description><![CDATA[Potentially mutagenic impurities in new pharmaceuticals are controlled to levels with negligible risk, the C (threshold of toxicological concern, 1.5 μg/day for a lifetime). The C was based on the...]]></description>
<pubDate>Sat, 18 May 2013 01:14:10 +0100</pubDate>
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<item>
<title>Mechanisms of P-gp inhibition and effects on membrane fluidity of a new rifampicin derivative, 1,8-dibenzoyl-rifampicin</title>
<link>http://scienceindex.com/stories/3121025/Mechanisms_of_Pgp_inhibition_and_effects_on_membrane_fluidity_of_a_new_rifampicin_derivative_18dibenzoylrifampicin.html</link>
<guid>http://scienceindex.com/stories/3121025/Mechanisms_of_Pgp_inhibition_and_effects_on_membrane_fluidity_of_a_new_rifampicin_derivative_18dibenzoylrifampicin.html</guid><description><![CDATA[To assess P-glycoprotein (P-gp)-modulation ability and the mechanisms of P-gp inhibition mediated by a new synthetic rifampicin derivative, 1,8-dibenzoyl-rifampicin (DiBenzRif), in an in vitro mode...]]></description>
<pubDate>Fri, 17 May 2013 23:07:17 +0100</pubDate>
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<item>
<title>Cytotoxic effects of incense particles in relation to oxidative stress, the cell cycle and F-actin assembly</title>
<link>http://scienceindex.com/stories/3121026/Cytotoxic_effects_of_incense_particles_in_relation_to_oxidative_stress_the_cell_cycle_and_Factin_assembly.html</link>
<guid>http://scienceindex.com/stories/3121026/Cytotoxic_effects_of_incense_particles_in_relation_to_oxidative_stress_the_cell_cycle_and_Factin_assembly.html</guid><description><![CDATA[Epidemiological studies have suggested that combustion-derived smoke, such as that produced during incense burning, is a deleterious air pollutant. It is capable of initiating oxidative stress and ...]]></description>
<pubDate>Fri, 17 May 2013 23:07:17 +0100</pubDate>
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<item>
<title>Bioaccumulation and neurotoxicity of dithiopyridine herbicide in the brain of freshwater fish, Cyprinus carpio</title>
<link>http://scienceindex.com/stories/3120984/Bioaccumulation_and_neurotoxicity_of_dithiopyridine_herbicide_in_the_brain_of_freshwater_fish_Cyprinus_carpio.html</link>
<guid>http://scienceindex.com/stories/3120984/Bioaccumulation_and_neurotoxicity_of_dithiopyridine_herbicide_in_the_brain_of_freshwater_fish_Cyprinus_carpio.html</guid><description><![CDATA[The freshwater carp, Cyprinus carpio, was exposed to 0.5 mg (30% of median lethal concentration (LC50)), 1.0 mg (60% of LC50), and 1.6 mg (LC50) of dithiopyridine herbicide per liter for acute (24 ...]]></description>
<pubDate>Fri, 17 May 2013 22:27:21 +0100</pubDate>
</item>
<item>
<title>Largazole, a class I histone deacetylase inhibitor, enhances TNF-α-induced ICAM-1 and VCAM-1 expression in rheumatoid arthritis synovial fibroblasts</title>
<link>http://scienceindex.com/stories/3120512/Largazole_a_class_I_histone_deacetylase_inhibitor_enhances_TNFinduced_ICAM1_and_VCAM1_expression_in_rheumatoid_arthritis_synovial_fibroblasts.html</link>
<guid>http://scienceindex.com/stories/3120512/Largazole_a_class_I_histone_deacetylase_inhibitor_enhances_TNFinduced_ICAM1_and_VCAM1_expression_in_rheumatoid_arthritis_synovial_fibroblasts.html</guid><description><![CDATA[In the present study, we evaluated the effect of largazole (LAR), a marine-derived class I HDAC inhibitor, on tumor necrosis factor-α (TNF-α)-induced expression of intercellular adhesion molecule...]]></description>
<pubDate>Fri, 17 May 2013 18:44:13 +0100</pubDate>
</item>
<item>
<title>Species-level study on arsenic availability from dietary components</title>
<link>http://scienceindex.com/stories/3120063/Specieslevel_study_on_arsenic_availability_from_dietary_components.html</link>
<guid>http://scienceindex.com/stories/3120063/Specieslevel_study_on_arsenic_availability_from_dietary_components.html</guid><description><![CDATA[Arsenic (As) contaminated water and foodstuffs are of major concern. Samples of drinking–cooking water (n = 50), raw rice (n = 50), common vegetables (eight types), and common pulses (three types...]]></description>
<pubDate>Fri, 17 May 2013 14:45:40 +0100</pubDate>
</item>
<item>
<title>Effect of Zinc Oxide nanoparticles on cellular oxidative stress and antioxidant defense mechanisms in mouse liver</title>
<link>http://scienceindex.com/stories/3120062/Effect_of_Zinc_Oxide_nanoparticles_on_cellular_oxidative_stress_and_antioxidant_defense_mechanisms_in_mouse_liver.html</link>
<guid>http://scienceindex.com/stories/3120062/Effect_of_Zinc_Oxide_nanoparticles_on_cellular_oxidative_stress_and_antioxidant_defense_mechanisms_in_mouse_liver.html</guid><description><![CDATA[Zinc oxide nanoparticles (ZnO2), a common ingredient of cosmetics has a huge variety of applications. Previous studies reported oxidative stress mediated toxicity of ZnO2 nanoparticles on various m...]]></description>
<pubDate>Fri, 17 May 2013 14:45:26 +0100</pubDate>
</item>
<item>
<title>Evaluation of the toxicity of tetrabromobisphenol A and some of its oxidation products using a micro-scale algal growth inhibition test</title>
<link>http://scienceindex.com/stories/3120061/Evaluation_of_the_toxicity_of_tetrabromobisphenol_A_and_some_of_its_oxidation_products_using_a_microscale_algal_growth_inhibition_test.html</link>
<guid>http://scienceindex.com/stories/3120061/Evaluation_of_the_toxicity_of_tetrabromobisphenol_A_and_some_of_its_oxidation_products_using_a_microscale_algal_growth_inhibition_test.html</guid><description><![CDATA[A micro-scale algal growth inhibition (μ-AGI) test using a common micro-plate based fluorometric detection was used to demonstrate the effects of humic substances (HSs) on the toxicity of tetrabro...]]></description>
<pubDate>Fri, 17 May 2013 14:45:16 +0100</pubDate>
</item>
<item>
<title>Dissolution and bioavailability enhancement of glyburide</title>
<link>http://scienceindex.com/stories/3120060/Dissolution_and_bioavailability_enhancement_of_glyburide.html</link>
<guid>http://scienceindex.com/stories/3120060/Dissolution_and_bioavailability_enhancement_of_glyburide.html</guid><description><![CDATA[The solubility behavior of drug is one of the most challenging aspects in formulation development, as dissolution and absorption behaviors depend upon this property. The objective of this study was...]]></description>
<pubDate>Fri, 17 May 2013 14:45:04 +0100</pubDate>
</item>
<item>
<title>Trichoderma harzianum: a green sorbent for Pb(II) uptake from aqueous solutions</title>
<link>http://scienceindex.com/stories/3120059/Trichoderma_harzianum_a_green_sorbent_for_PbII_uptake_from_aqueous_solutions.html</link>
<guid>http://scienceindex.com/stories/3120059/Trichoderma_harzianum_a_green_sorbent_for_PbII_uptake_from_aqueous_solutions.html</guid><description><![CDATA[This investigation describes the use of specially cultivated, nonliving biomass of Trichoderma harzianum as a biosorbent for the batch removal of Pb(II) from a stirred system under different experi...]]></description>
<pubDate>Fri, 17 May 2013 14:44:56 +0100</pubDate>
</item>
<item>
<title>Modified cross-linked polyethylenimine for the removal of selenite from mining wastewaters</title>
<link>http://scienceindex.com/stories/3120058/Modified_crosslinked_polyethylenimine_for_the_removal_of_selenite_from_mining_wastewaters.html</link>
<guid>http://scienceindex.com/stories/3120058/Modified_crosslinked_polyethylenimine_for_the_removal_of_selenite_from_mining_wastewaters.html</guid><description><![CDATA[Cross-linked branched polyethylenimine (CPEI) was sulfonated by reaction with 3-chloropropanesulfonyl chloride. The functionalized polymer was used as an adsorbent for the removal of SeO32− from ...]]></description>
<pubDate>Fri, 17 May 2013 14:44:50 +0100</pubDate>
</item>
<item>
<title>Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays</title>
<link>http://scienceindex.com/stories/3119078/Profiling_976_ToxCast_Chemicals_across_331_Enzymatic_and_Receptor_Signaling_Assays.html</link>
<guid>http://scienceindex.com/stories/3119078/Profiling_976_ToxCast_Chemicals_across_331_Enzymatic_and_Receptor_Signaling_Assays.html</guid><description><![CDATA[Understanding potential health risks is a significant challenge due to the large numbers of diverse chemicals with poorly characterized exposures and mechanisms of toxicities. The present study ana...]]></description>
<pubDate>Fri, 17 May 2013 07:37:41 +0100</pubDate>
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<item>
<title>Flumequine enhances the in vivo mutagenicity of MeIQx in the mouse liver</title>
<link>http://scienceindex.com/stories/3118633/Flumequine_enhances_the_in_vivo_mutagenicity_of_MeIQx_in_the_mouse_liver.html</link>
<guid>http://scienceindex.com/stories/3118633/Flumequine_enhances_the_in_vivo_mutagenicity_of_MeIQx_in_the_mouse_liver.html</guid><description><![CDATA[The combined effects of various carcinogens found in food products are a concern for human health. In the present study, the effects of flumequine (FL) on the in vivo mutagenicity of 2-amino-3,8-di...]]></description>
<pubDate>Fri, 17 May 2013 04:53:19 +0100</pubDate>
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