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More than bindin divergence: reproductive isolation between sympatric subspecies of a sea urchin by asynchronous spawning
submitted by BraAdrie 1 hour ago
The evolution of reproductive barriers is crucial to the process of speciation. In the Echinoidea, studies have focused on divergence in the gamete recognition protein, bindin, as the primary isolating mechanism among species. As such, the capacity of alternate mechanisms to be effective reproduc...
 


Connecting the dots of nonlinear reaction norms unravels the threads of genotype-environment interaction in drosophila
submitted by jinnefir 1 hour ago
Two contrasting views can characterize the attitude of many studies towards reaction norms (RN). An “optimistic” view attempts to use a linear model to describe RN variation; and a “pessimistic” view emphasizes RNs complexity without using any model to describe them. Here, we have analyze...
 
Proteomic changes in response to potassium starvation in the extremophilic yeast Debaryomyces hansenii
submitted by rochilt4ak 1 hour ago
In this work we performed for the first time a proteomic approach to the processes induced by long-term potassium starvation in the halotolerant yeast Debaryomyces hansenii. The proteomic profile under this ionic stress conditions shows that important changes in gene expression take place as an a...
 
Effects of probiotics, probiotic DNA and the CpG oligodeoxynucleotides on ovalbumin-sensitized Brown-Norway rats via TLR9/NF-κB pathway
submitted by DustJunior 1 hour ago
The aim of the study was to investigate the effect of living probiotics, probiotic DNA and the synthetic oligodeoxynucleotides containing CpG motifs (CpG-ODN) on both immune response and intestinal barrier function in ovalbumin-sensitized rat and the underlying mechanisms. Brown-Norway rats were ...
 


Immune Stimulating and Therapeutic Potential of Tuftsin-incorporated Nystatin Liposomes against Cryptococcus neoformans in Leukopenic BALB/C mice
submitted by AsaJah 1 hour ago
A Cryptococcus neoformans infection is a common fungal infection in persons infected with human immune deficiency virus (HIV) or in persons with defective cell-mediated immunity. Since treatment of cryptococcal meningitis poses a big challenge, present study was aimed to develop a novel liposomal...
 
A one dose experimental cholera vaccine
submitted by omoloa 1 hour ago
The number of cholera vaccine doses required for immunity is a constraint during epidemic cholera. Protective immunity following one dose of multiple Vibrio cholerae (Vc) colonization factors (Inaba LPS El Tor, TcpA, TcpF, and CBP-A) has not been directly tested in even though individual Vc colon...
 
Lipopolysaccharide O-antigen of Enterohemorrhagic Escherichia coli O157:H7 is required for killing both insects and mammals
submitted by xbb 1 hour ago
Studies of Enterohemorrhagic Escherichia coli (EHEC) infection mechanisms using mammals require large numbers of animals and are both costly and associated with ethical problems. Here we evaluated the pathogenic mechanisms of EHEC in the silkworm model. Injection of a clinically isolated EHEC O15...
 
Comparative analysis of P2-type remnant prophage loci in Xenorhabdus bovienii and Xenorhabdus nematophila required for xenorhabdicin production
submitted by leno6691 1 hour ago
The xnp1 remnant P2-type prophage of Xenorhabdus nematophila produces xenorhabdicin that is active against closely related species. Xenorhabdicin had not been characterized previously in other Xenorhabdus species. Here we show xenorhabdicin production in six different strains of X. bovienii. The ...
 
Local activation of cardiac stem cells for post-myocardial infarction cardiac repair
submitted by doneil10 1 hour ago
The prognosis of patients with myocardial infarction (MI) and resultant chronic heart failure remains extremely poor despite continuous advancements in optimal medical therapy and interventional procedures. Animal experiments and clinical trials using adult stem cell therapy following MI have sho...
 
Placental mesenchymal dysplasia and an estimation of the population incidence
submitted by amoerahs 1 hour ago
Placental mesenchymal dysplasia (PMD) is a rare placental malformation of as yet undetermined etiology. We report a single center's experience of this diagnosis and present an estimation of the population incidence. Within our institution, all placentae are examined within a pathology department ...
 
Predictive score for early preterm birth in decisions about emergency cervical cerclage in singleton pregnancies
submitted by jhn84wllms 1 hour ago
To develop a simple score for assessing the risk of early preterm delivery before 32 weeks in women with singleton pregnancies receiving emergency cervical cerclage. Retrospective study. French tertiary care center from 1994 to 2006. Population. A total of 134 pregnant women underwent emergency c...
 
Maternal lipids at mid-pregnancy and the risk of preterm delivery
submitted by mecragay 1 hour ago
This study examined associations between maternal lipid levels at mid-pregnancy and preterm delivery, medically indicated or spontaneous. Prospective cohort study. Women were recruited from 52 clinics in five Michigan, USA communities (1998–2004). Population. Pregnant women were enrolled at 15...
 
Alcohol prevention in Swedish antenatal care: effectiveness and perceptions of the Risk Drinking project counseling model
submitted by doleo3119 1 hour ago
To compare an earlier Swedish antenatal care counseling routine concerning alcohol consumption with an expanded model in terms of effectiveness in achieving abstinence in pregnancy. A further objective was to assess the women's perceptions of the alcohol counseling. Cohort study. Antenatal care c...
 
Long-term outcome after obstetric injury: a retrospective study
submitted by jwoezil 1 hour ago
To examine problems experienced by women after vaginal delivery with and without a sphincter tear and compare those with less and more severe injuries. Retrospective questionnaire study. Regional hospital in Sweden. Sample. A total of 324 women with and 309 without sphincter tears. Methods. Quest...
 
Clinical and economic impact of adhesiolysis during repeat cesarean delivery
submitted by eaon 1 hour ago
To estimate adhesiolysis rates at cesarean delivery (CD) and to estimate costs and clinical implications of performing adhesiolysis at repeat CD. Retrospective cohort using secondary data. Over 500 acute care hospitals in the USA. Population. Women ≥15 years old with a medical claim for CD betw...
 
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