Psychiatry

Vers une psychiatrie cognitive de remédiation sur le modèle de la médecine physique et de réadaptation
L’efficacité réelle mais incomplète et inconstante des psychotropes a longtemps confronté le modèle de soin à la question de la réinsertion et de la prise en compte des symptômes résiduels des patients. Depuis une trentaine d’années, l’évolution des connaissances théoriques sur les troubles psychiques, tant au plan de la psychopathologie que des connaissances fondamentales, a ...


Courses of helping alliance in the treatment of people with severe mental illness in Europe: a latent class analytic approach
The helping alliance (HA) between patient and therapist has been studied in detail in psychotherapy research, but less is known about the HA in long-term community mental health care. The aim of this study was to identify typical courses of the HA and their predictors in a sample of people with severe mental illness across Europe over a measurement period of one year. Self-ratings of the HA by ...
A Systematic Review and Meta-Analysis of Cognitive-Behavioral Therapy for Anxiety in Youth with High-Functioning Autism Spectrum Disorders
Cognitive-behavioral therapy (CBT) has been developed and modified to treat anxiety symptoms in youth with high-functioning autism spectrum disorders (ASD) but has yielded varying findings. The present report is a systematic review and meta-analysis examining the efficacy of CBT for anxiety among youth with ASD. A systematic search identified 14 studies involving 511 youth with high-functioning...


Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia
Aberrant DNA methylation and gene expression have been reported in postmortem brain tissues of psychotic patients, but until now there has been no systematic evaluation of synergistic changes in methylation and expression on a genome-wide scale in brain tissue. In this study, genome-wide methylation and expression analyses were performed on cerebellum samples from 39 patients with schizophrenia...
Cognitive changes in patients with acute phase psychosis—Effects of illicit drug use
Illicit drug use may influence cognition in non-affective psychosis. Previous studies have shown better cognition in psychosis with illicit drug use as compared to psychosis only. Possibly, illicit drug using patients have more transient drug-related cognitive deficits. Thus, the aim of the present study was to examine cognitive change the first weeks after admission to a psychiatric emergency ...


Anxiety Disorders and Obsessive Compulsive Disorder Nine Months after Perinatal Loss
Perinatal loss (stillbirth after 20weeks gestational age or infant death in the first month) impacts 1–2 infants per hundred live births in the United States and can be a devastating experience for parents. We assessed prevalence of anxiety disorders and obsessive compulsive disorder (OCD) among bereaved and live-birth mothers. We collaborated with the Michigan Department of Public Health to ...
Double attention bias for positive and negative emotional faces in clinical depression: Evidence from an eye-tracking study
According to cognitive models, attentional biases in depression play key roles in the onset and subsequent maintenance of the disorder. The present study examines the processing of emotional facial expressions (happy, angry, and sad) in depressed and non-depressed adults. Sixteen patients with Major Depressive Disorder (MDD) and 34 never-depressed controls (ND) completed an eye-tracking task to...

Validation of a brief implicit association test of stigma: schizophrenia and dangerousness
Public perception of the link between schizophrenia and violence is exaggerated, and interventions are emerging that attempt to educate the public about the actual relationship between violence and schizophrenia. The effectiveness of programs targeting this dangerousness stereotype is unknown, however, as existing instruments do not capture a complete, unbiased picture of stigma. To report on t...
Content and implementation of clinical decisions in the routine care of people with severe mental illness
Clinical decision making (CDM) in the treatment of people with severe mental illness relates to a wide range of life domains. To examine content of CDM in mental health care from the perspectives of service users and staff and to investigate variation in implementation of decisions for differing content. As part of the European multicenter study clinical decision making and outcome in routine c...

Prevalence and Clinical Correlates of Obsessive - Compulsive Disorder in Schizophrenia
Obsessive compulsive symptoms frequently occur in a substantial proportion of patients with schizophrenia. The term schizoobsessive has been proposed to delineate this subgroup of schizophrenia patients who present with obsessive-compulsive symptoms/disorder. However, whether this co-occurrence is more than just co-morbidity and represents a distinct subgroup remains controversial. A striking v...
Psychometric properties of a Chinese version of the Stigma Scale: examining the complex experience of stigma and its relationship with self-esteem and depression among people living with mental illness in Hong Kong
Stigma of mental illness is a global public health concern, but there lacks a standardized and cross-culturally validated instrument for assessing the complex experience of stigma among people living with mental illness (PLMI) in the Chinese context. This study examines the psychometric properties of a Chinese version of the Stigma Scale (CSS), and explores the relationships between stigma, sel...

Prenatal nicotine exposure and child behavioural problems
In utero exposure to tobacco smoke has been related to numerous adverse health effects in new-borns, infants, children, adolescents and adults. The aim of this review was to summarise findings on prenatal nicotine exposure and its relationship with behavioural problems in the offspring. The majority of studies, and especially several recent epidemiological studies, observed a higher likelihood ...
Experience Processing as an Aspect of Existential Psychotherapy: Life Enhancement Methodology
The paper presents an existential methodology of life enhancement that can be applied both in the context of an existential psychotherapy session and in a non-therapeutic setting. The prototype of life enhancement is ontogogy, conceptualized by Jim Bugental as the second stage of the psychotherapeutic process. The process, targets and outcomes of life enhancement work are discussed, as well as ...
Structural Existential Analysis (SEA): A Phenomenological Method for Therapeutic Work
Phenomenology has inspired many forms of therapeutic practice over the past century. This paper summarizes fundamental aspects of phenomenological practice, which are often forgotten. It covers phenomenological, eidetic and transcendental reductions and briefly introduces other aspects of structural existential analysis such as four worlds model, timeline, and emotional compass. The work is bro...
Frequency and Clinical Correlates of Sleep-Related Problems Among Anxious Youth with Autism Spectrum Disorders
Sleep-related problems (SRPs) are common and problematic among anxious youth but have not been investigated in anxious youth with autism spectrum disorder (ASD). Participants were 102 youth (ages 7–16 years) with ASD and comorbid anxiety. Youth and their primary caregiver were administered the Pediatric Anxiety Rating Scale. Parents completed the Multidimensional Anxiety Scale for Children...