Psychiatry

NMDA receptor antagonists interventions in schizophrenia: Meta-analysis of randomized, placebo-controlled trials
We examined whether N-methyl d-aspartate (NMDA) receptor antagonists as adjunctive therapy have therapeutic potential for schizophrenia treatment. Systematic review of PubMed, Cochrane Library, PsycINFO and Google Scholar up until October 2012 and meta-analysis of randomized placebo-controlled tr...


Simple measures and complex structures: Is it worth employing a more complex model of personality in Big Five inventories?
The poor performance of five-factor personality inventories in confirmatory factor analyses (CFA) prompted some to question their construct validity. Others doubted the CFA’s suitability and suggested applying Exploratory Structural Equation Modeling (ESEM). The question arises as to what impac...
Personality and psychopathology: Higher order relations between the Five Factor Model of personality and the MMPI–2 Restructured Form
This study investigates the relationship between personality and psychopathology as measured by the NEO Personality Inventory (Costa McCrae, 1992) and the Minnesota Multhiphasic Personality Inventory–2–Restructured Form (MMPI–2–RF; Ben-Porath Tellegen, 2008) in a combined dataset of patie...
Structural and functional cortical disconnection in Alzheimer's disease: A combined study using diffusion tensor imaging and transcranial magnetic stimulation
We investigated the functional consequences of compromised white matter integrity in Alzheimer's disease by combining Diffusion Tensor Imaging (DTI) and Transcranial Magnetic Stimulation (TMS) in 19 patients with AD (Alzheimer's disease) and 19 healthy controls. We used a region of interest appro...
White matter microstructural abnormalities in patients with late-onset schizophrenia identified by a voxel-based diffusion tensor imaging
Reduced fractional anisotropy (FA) has been previously found in diffusion tensor imaging (DTI) studies of white matter in schizophrenic patients. However, there are no reports in the literature that address FA alterations in late-onset schizophrenia (LOS). The current study measured FA in whole w...
Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression
The serotonin transporter (SERT) is hypothesized to be an important component of the pathophysiology of major depression (MD). The aim of this study was to use [123I]ADAM single-photon emission computed tomography (SPECT) to explore whether SERT availability in four regions of the brain (striatum...


Don’t just repeat after me: Retrieval practice is better than imitation for foreign vocabulary learning
Second language (L2) instruction programs often ask learners to repeat aloud words spoken by a native speaker. However, recent research on retrieval practice has suggested that imitating native pronunciation might be less effective than drill instruction, wherein the learner is required to produc...
Knowledge on the line: Manipulating beliefs about the magnitudes of symbolic numbers affects the linearity of line estimation tasks
It has been suggested that differences in performance on number-line estimation tasks are indicative of fundamental differences in people’s underlying representations of numerical magnitude. However, we were able to induce logarithmic-looking performance in adults for magnitude ranges over whic...
Interaction between a serotonin transporter gene promoter region polymorphism and stress predicts depressive symptoms in Chinese adolescents: a multi-wave longitudinal study
The serotonin transporter (5-H) gene may play an important role in the onset and development of mental disorders. Past studies have tested whether a functional polymorphism in the 5-H gene linked promoter region (5-HLPR) moderated the association between stress and depressive symptoms, but the re...
Psychiatric disorder prevalence among deaf and hard-of-hearing outpatients
To contribute to the dearth of literature on the prevalence rates of psychiatric disorders in deaf adults, this study examined the diagnostic and clinical characteristics of deaf psychiatric outpatients in comparison to hearing psychiatric outpatients. Archival clinical data for deaf adults (N=24...
Clinical Application of Actigraphy in Psychotic Disorders: A Systematic Review
Actigraphy has become increasingly recognized as a useful method to study sleep/wake patterns and activity monitoring. It is a reliable tool for confirming a diagnosis and evaluating the effect of treatments for sleep problems in patients with primary psychiatric diagnoses such as schizophrenia. ...


Learning disorder and blood concentration of heavy metals in the United Arab Emirates
Children are frequently exposed to toxic metals in the environment, and their developing central nervous system is particularly vulnerable to their effects. This study examined the blood level of heavy metals in children with learning disorder (LD) as compared to children without LD in the United...
Symptoms and treatment of mental illness among prisoners: A study of Michigan state prisons
This study reports on a representative sample of prisoners in Michigan correctional facilities to determine the prevalence of psychiatric illness and the delivery of mental health (MH) services. Mental health assessments were conducted with 618 incarcerated subjects using the interRAI Correctiona...
Personality Stability from Childhood to Midlife: Relating Teachers’ Assessments in Elementary School to Observer- and Self-Ratings 40 Years Later
We report on the longitudinal stability of personality traits across an average 40 years in the Hawaii Personality and Health Cohort relating childhood teacher assessments of personality to adult self- and observer- reports. Stabilities based on self-ratings in adulthood were compared to those me...
The relevance of self-esteem and self-schemas to persecutory delusions: A systematic review
Self-esteem is frequently targeted in psychological approaches to persecutory delusions (PD). However, its precise role in the formation and maintenance of PD is unclear and has been subject to a number of theories: It has been hypothesized that PD function to enhance self-esteem, that they direc...