submitted by mizshf 1 hour ago
Un patient caucasien de 19ans, sans antécédent notable, a consulté devant la découverte d’une masse du testicule droit apparue un mois auparavant. L’examen clinique ne retrouvait pas de gynécomastie ni de pigmentation cutanée anormale. Les taux sanguins d’alpha-fœtoprotéine, de test...
submitted by yomco 2 hours ago
IL-18 is an immune-stimulating cytokine that promotes experimental melanoma metastasis via vascular endothelial growth factor (VEGF)–induced very late antigen (VLA)-4. We studied genes associated with the ability of melanoma cells to allow metastasis under IL-18 effects, and we verified their e...
submitted by bhorads423 7 hours ago
Fusarium oxysporum (Schlechtend.: Fr.) f. sp. melongenae (Fomg) recovered from symptomatic eggplants from five eggplant-growing areas in Turkey, including the south, west, north-west, north and south-east regions. The objective of this study was to investigate the genetic diversity of the Fomg i...
submitted by DaviIsa 7 hours ago
Moisture variables have not been a consistent predictor of Rhizoctonia web blight development on container-grown azalea. A vapour pressure deficit ...
submitted by rosho622 9 hours ago
This study is to investigate the expression of progranulin (PGRN) in systemic lupus erythematosus (SLE) patients and the effect of glucocorticoid (GC) treatment on its expression. Thirty newly diagnosed severe SLE patients and 30 healthy subjects were enrolled in this study. The serum levels of P...
submitted by EliaLanden 9 hours ago
Oral lichen planus (OLP) is a potentially malignant disorder associated with an increased risk of oral squamous cell carcinoma (OSCC). The objective of this study was to determine protein expression of cancer stem cell marker aldehyde dehydrogenase 1 (ALDH1) in a series of patients with OLP and e...
submitted by tetobarnhom 9 hours ago
In this study, the protein levels of Axl and prostasin in malignant neoplasms of the ovary and their clinicopathologic significance were investigated. The protein levels of Axl and prostasin in ovarian adenocarcinomas (n = 80), serous cystadenoma (n = 15), mucinous cystadenomas (n = 15), and norm...
submitted by likhoeli 11 hours ago
Research in the field of cancer immunity, which is of increasing credence, suggests that cancer is a disorder that manifests with characteristics also present in reproductive physiology-effectively a somatic cell pregnancy. This paradigm complements the conventional somatic mutation theory, propo...
submitted by rofeom 11 hours ago
Clonal expansion of lymphocytes may account for asymptomatic lymphocytosis. Unlike monoclonal B lymphocytosis, the detection of T-cell clones is difficult using immunophenotype-based assays. This study aimed to evaluate PCR-based clonality assays for the identification of T-cell clones among pati...
submitted by doneil10 11 hours ago
To compare the accuracy of eyeball estimates of the Ki-67 proliferation index (PI) with formal counting of 2000 cells as recommend by the Royal College of Pathologists. Sections from gastroenteropancreatic neuroendocrine tumours were immunostained for Ki-67. PI was calculated using three methods:...
submitted by drroe 11 hours ago
We read with great interest the article by Salinas et al suggesting the use of the icteric index (II) as a front-line test for the preliminary identification of blood samples with abnormal total bilirubin (TB) concentrations. Following the authors’ suggestion, we were encouraged to experime...
submitted by yfronq 11 hours ago
Mutations of the fms-like tyrosine kinase 3 (FLT3) gene located at chromosome 13q12, alone or in combination with other oncogene mutations, occur in approximately 40% of cases of acute myeloid leukaemia (AML). Two major types of FLT3 mutations have been identified: (1) internal tandem duplication...
submitted by spedirmon83 11 hours ago
Pulmonary fibrosis in surgical lung biopsies is said to have a ‘usual interstitial pneumonia-pattern’ (UIP-pattern) of disease when scarring of the parenchyma is present in a patchy, ‘temporally heterogeneous’ distribution. These biopsies are one of the more common non-neo...
submitted by XzavierNi 13 hours ago
Ewing sarcoma (ES) is an aggressive malignant small round cell tumor that arises in bone or soft tissue of adolescents and young adults. A characteristic molecular finding in ES is EWSR1 gene fusion with ETS (erythroblast transformation-specific) family genes including FLI1 (~90%) and ERG (&g...
submitted by SanTony 13 hours ago
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) consists of a heterogeneous group of lymphomas. Patients generally show an aggressive clinical course and very poor outcome. Although the 2008 World Health Organization classification of PTCL-NOS includes 3 variants, low-grade lymphom...