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Medicine

Pulmonary sarcoidosis
submitted by pomilo 9 hours ago
This latter is associated with a higher mortality rate due to various forms of sarcoid-related pulmonary vasculopathy. Treatment options include epoprostenol, sildenafil or bosentan. Lung transplan...
 


Pneumonia
submitted by horclo 9 hours ago
This article addresses many of these management issues with reference to changes in management for particular patient groups. The importance of stratifying risk and immediate emergency department m...
 
Pneumoconiosis
submitted by alorad 9 hours ago
(CWP) is directly due to the effects of both coal and stone dust, and may be simple or complicated. Often regarded as a historic disease, new cases continue to occur. Most cases do not progress bey...
 
Diffuse parenchymal lung disease
submitted by krsch 9 hours ago
(DPLDs) are a group of over 200 diverse conditions all of which affect either the alveolar space or the pulmonary interstitium. All DPLDs typically present with dyspnoea and diffuse infiltrates on ...
 


Respiratory failure
submitted by rozon44 9 hours ago
Is defined as a partial pressure of arterial oxygen (PaO2) less than 8.0 kPa, and type 2 respiratory failure (hypercapnic respiratory failure) as PaO2 less than 8 kPa and a partial pressure of arte...
 
Obstructive sleep apnoea
submitted by amakora 9 hours ago
Occurs during sleep, when there is repeated pharyngeal collapse obstructing the airway, and causing repeated awakenings from sleep. Sufferers complain of unrefreshing sleep and daytime somnolence, ...
 
The sleepy patient
submitted by bshodi 9 hours ago
May be experiencing interrupted sleep caused by sleep-disordered breathing (i.e. obstructive sleep apnoea), periodic limb movements of sleep, or disease (e.g. arthritis or obstructive lung disease)...
 
High-Throughput Sequencing Detects Minimal Residual Disease in Acute T Lymphoblastic Leukemia
submitted by TerrOsca 1 day ago
High-throughput sequencing (HTS) of lymphoid receptor genes is an emerging technology that can comprehensively assess the diversity of the immune system. Here, we applied HTS to the diagnosis of T-...
 
Gene Therapy for Aromatic L-Amino Acid Decarboxylase Deficiency
submitted by sarish 1 day ago
Aromatic l-amino acid decarboxylase (AADC) is required for the synthesis of the neurotransmitters dopamine and serotonin. Children with defects in the AADC gene show compromised development, partic...
 
Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model
submitted by MarMathias 1 day ago
Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military vete...
 
Drug-Based Optical Agents: Infiltrating Clinics at Lower Risk
submitted by DandFra 1 day ago
Fluorescent agents with specificity to cellular and subcellular moieties present promise for enhancing diagnostics and theranostics, yet challenges associated with regulatory approvals of experimen...
 
Electrocardiographic Diagnosis of Acute ST-elevation Myocardial Infarction in the Presence of Left Bundle Branch Block
submitted by CarIan 1 day ago
This lecture can be viewed in its entirety online by visiting http://vimeo.com/34634434.ACADEMIC EMERGENCY MEDICINE 2012; 19:593
 
Mortality of HIV-infected and uninfected children in a longitudinal cohort in rural south-west Uganda during 8 years of follow-up
submitted by ohoih 1 day ago
To determine the impact of HIV on child mortality and explore potential risk factors for mortality among HIV-infected and HIV-exposed uninfected children in a longitudinal cohort in rural Uganda.Me...
 
Lisinopril pharmacokinetics and erythropoietin requirement in hemodialysis patients
submitted by paddeng 1 day ago
There is ongoing controversy whether angiotensin converting enzyme inhibitors (ACE-I) contribute to anemia by causing hyporesponsiveness to erythropoiesis stimulating agents (ESA). However, it is u...
 
Novel Dual Inhibitors of Vascular Endothelial Growth Factor and VEGFR2 Receptor
submitted by prencib5mi 1 day ago
Vascular endothelial growth factor (VEGF) helps control tumor growth via causing new capillaries growth in tumors. Four cardiac hormones (i.e. vessel dilator, long-acting natriuretic peptide (LANP)...
 

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