Medicine

Association of Genetic Variants in and Promoter Hypermethylation of CDH1 With Gastric Cancer: A Meta-Analysis
Gastric cancer (GC) is a common cause of cancer-related death. The etiology and pathogenesis of GC remain unclear, with genetic and epigenetic factors playing an important role. Previous studies investigated the association of GC with many genetic variants in and promoter hypermethylation of E-cadherin gene (CDH1), with conflicting results reported. To clarify this inconsistency, we conducted u...


Cortical Metabolic Arrangement During Olfactory Processing: Proposal for a 18F FDG PET/CT Methodological Approach
The aim of this article is to investigate the cortical metabolic arrangements in olfactory processing by using 18F fluorodeoxyglucose (FDG) positron emission tomography/computed tomography. Twenty-six normosmic individuals (14 women and 12 men; mean age 46.7 ± 10 years) were exposed to a neutral olfactory condition (NC) and, after 1 month, to a pure olfactory condition (OC) in a relatively...
Fecal Microbiota Transplantation in Inflammatory Bowel Disease: Beyond the Excitement
The purpose of this article is to perform a systematic review of the literature on the use of fecal microbiota transplantation (FMT) in inflammatory bowel disease (IBD). There is an increasing interest of both physicians and patients in assessing the possible role of the FMT in the treatment of IBD. Electronic and manual bibliographic searches were performed to identify original reports in whic...


The Morphologic Identification of Common Organisms That May Look Alike in the General Pathology Practice: A Brief Review
Surgical Pathologists often rely on morphologic features in identifying organisms in their general practice. The aim of this paper is to provide a brief practical and illustrated reference, comparing the morphologic features of organisms commonly encountered in the general practice of pathology. This comparison will focus on pairs of organisms that may look alike, resulting in diagnostic diffic...
Public engagement in priority-setting: Results from a pan-Canadian survey of decision-makers in cancer control
Decision-makers are challenged to incorporate public input into priority-setting decisions. We conducted a pan-Canadian survey of decision-makers in cancer control to investigate the types of evidence, especially evidence supplied by the public, that are utilized in health care priority-setting. We further examined how normative attitudes and contextual factors influence the use of public engag...


Racial/ethnic residential segregation, neighborhood poverty and urinary biomarkers of diet in New York City adults
Consuming less sodium and more potassium are components of a healthy diet and reduced cardiovascular disease risk. Racial/ethnic segregation and poverty are both associated with dietary habits, but data linking dietary intake to neighborhood characteristics are limited, particularly in Hispanic and Asian American ethnic enclaves. This study presents relationships between neighborhood-level segr...
How do dual practitioners divide their time? The cases of three African capital cities
Health professionals dual practice has received increasing attention, particularly in the context of the universal health coverage movement. This paper explores the determinants of doctors' choices to become a dual practitioner and of dual practitioners' choices to allocate time to the private sector in the capital cities of Mozambique, Guinea Bissau and Cape Verde. The data are drawn from a su...

The National Health Insurance Scheme in Ghana's Upper West Region: A gendered perspective of insurance acquisition in a resource-poor setting
Ghana's National Health Insurance Scheme (NHIS) was designed as a pro-poor strategy to create wider access to health care. While recent studies have shown that wealth is an important factor in enrolment in the scheme, there is little understanding of its interlinkages with the geographical divisions and deep-seated deprivation in the northern region. In response to the nexus of poverty, gender ...
Politics drives human functioning, dignity, and quality of life
Too little is known about human functioning amidst chronic adversity. We addressed that need by studying adult Palestinians in the occupied Palestinian territories (oPt), a population that has experienced longstanding economic and political hardships. Fourteen group interviews were conducted in February, 2010 in Arabic by local fieldworkers with 68 participants representing the main stratificat...

A Polymorphism in the Promoter Region of the Survivin Gene is Related to Hemorrhagic Transformation in Patients with Acute Ischemic Stroke
Hemorrhagic transformation (HT) of cerebral infarction is a common and serious occurrence following acute ischemic stroke. The expression of survivin, a member of the inhibitor of apoptosis protein family, has been shown to increase after cerebral ischemia. This protein has been mainly located at the microvasculature within the infarcted and peri-infarcted area, so we aimed to investigate wheth...
Learning from biology: synthetic lipoproteins for drug delivery
Synthetic lipoproteins represent a relevant tool for targeted delivery of biological/chemical agents (chemotherapeutics, siRNAs, photosensitizers, and imaging contrast agents) into various cell types. These nanoparticles offer a number of advantages for drugs delivery over their native counterparts while retaining their natural characteristics and biological functions. Their ultra-small size (...

Medication Adherence in Secondary Prevention Post-Myocardial Infarction
Nonadherence to cardiovascular medications is common and has been associated with adverse outcomes. Patient adherence to medications is complex, with multiple factors contributing to the development of nonadherence, and these factors likely evolve over time. Significant efforts have gone into identifying factors that impact patient adherence, including patient, physician, and social/environment...
Comparison of self-report sleep measures for individuals with multiple sclerosis and spinal cord injury
To investigate self-report measures of sleep disturbances and sleep-related impairments in samples of individuals with multiple sclerosis (MS) or spinal cord injury (SCI) Cross-sectional survey. Community-based Adults (age 18 and older) with either MS (N=461) or SCI (N=239) who were enrolled in a longitudinal survey of self-reported health outcomes and who completed self-report sleep measures a...
Preliminary Evidence to Support a ‘Boot Camp’ Approach to Wheelchair Skills Training for Clinicians
To evaluate the impact of providing intensive large-group training on wheelchair-specific self-efficacy and skill capacity among occupational therapy students. Intervention study using before-after trial. Two Canadian universities Volunteer sample of 65 Master of Occupational Therapy students. Two instructors provided a total of 4.5 hours of wheelchair skills training to groups of 14 – 19 stu...
Treatment of detrusor external sphincter dyssynergia using ultrasound-guided trocar catheter transurethral botulinum toxin A injection in male patients with spinal cord injury
This study aimed to evaluate the effects of transrectal ultrasound-guided trocar catheter transurethral botulinum toxin A injection into the external urethral sphincter for treating detrusor external sphincter dyssynergia in male patients with spinal cord injury. Descriptive study. Hospital rehabilitation department. Patients (N=15; age 40.5; range 22–64y) with suprasacral spinal cord injury ...