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The effect of Q Factor on gross mechanical efficiency and muscular activation in cycling

submitted by skaalva 1 hour ago

Unexplored in scientific literature, Q Factor describes the horizontal width between bicycle pedals and determines where the foot is laterally positioned throughout the pedal stroke. The aim of the...

1 dig(s) Dig it Bury Topic: Immunology

Effect of cooling during inter-exercise periods on subsequent intramuscular water movement and muscle performance

submitted by moysen 1 hour ago

To evaluate the effects of cooling between exercise sessions on intramuscular water movement and muscle performance, the lower extremities of nine untrained men were assigned to either a cooling pr...

1 dig(s) Dig it Bury Topic: Immunology

Clinical, molecular, and cellular immunologic findings in patients with SP110-associated veno-occlusive disease with immunodeficiency syndrome

submitted by krsch 9 hours ago

Mutations in the SP110 gene result in infantile onset of the autosomal recessive primary immunodeficiency disease veno-occlusive disease with immunodeficiency syndrome (VODI), which is characterize...

1 dig(s) Dig it Bury Topic: Immunology

Comparative Genomics Analysis of Five Families of Antimicrobial Peptide-Like Genes in Seven Ant Species

submitted by rozon44 10 hours ago

Ants, as eusocial insects, live in dense groups with high connectivity, increasing the risk of pathogen spread and possibly driving the evolution of their antimicrobial immune system. Draft genomes...

1 dig(s) Dig it Bury Topic: Immunology

Rationale for accuracy and consistency in applying standardized definitions for surveillance of health care–associated infections

submitted by grenzy 11 hours ago

As legislative mandates for disclosure of data on health care–associated infections (HAIs) to the public escalate, with both economic and reputational implications for hospitals, the development ...

1 dig(s) Dig it Bury Topic: Immunology

Fusidic acid for the treatment of bone and joint infections caused by meticillin-resistant Staphylococcus aureus

submitted by AedSco 21 hours ago

There is a lack of surveillance data on resistance to fusidic acid (FA) in Asia, and no reviews of FA usage for the treatment of orthopaedic infections have been conducted since the year 2000. In t...

1 dig(s) Dig it Bury Topic: Immunology

Immunity to fungi

submitted by TyeJere 22 hours ago

Toll-like receptor agonism can resolve fungal infections. IL-17 is a key mediator of antifungal immunity, particularly at mucosal surfaces. Experimental fungal vaccines elicit protective immunity b...

1 dig(s) Dig it Bury Topic: Immunology

T cell tolerance and immunity to commensal bacteria

submitted by morgi 22 hours ago

The commensal bacteria normally resident in the gastrointestinal tract represent an enormous pool of foreign antigen within the body. Although mechanical barriers limit entry of bacteria into the h...

1 dig(s) Dig it Bury Topic: Immunology

Protection versus pathology in tuberculosis: recent insights

submitted by jimohall4590 22 hours ago

Recent studies have revisited the roles of prime players in the immune response to tuberculosis (TB) and have highlighted novel functions of these players. Specifically, immunoregulatory mechanisms...

1 dig(s) Dig it Bury Topic: Immunology

Comparative clinical evaluation of the IsoAmp® HSV Assay with ELVIS® HSV culture/ID/typing test system for the detection of herpes simplex virus in genital and oral lesions

submitted by lilybush 1 day ago

The novel IsoAmp® HSV Assay employs isothermal helicase-dependent nucleic acid amplification and a user-friendly disposable test device to achieve rapid (<1.5h), on-demand qualitative detection...

1 dig(s) Dig it Bury Topic: Immunology

Molecular evidence of St. Louis encephalitis virus infection in patients in Buenos Aires, Argentina

submitted by kvraam32 1 day ago

We report two cases of St. Louis encephalitis where the virus was detected in patients’ sera directly by molecular techniques allowing subsequent typing. Phylogenetic analysis of both samples sho...

1 dig(s) Dig it Bury Topic: Immunology

Interleukin-33 and the function of innate lymphoid cells

submitted by WesleMike 1 day ago

Interleukin (IL)-33 is a member of the IL-1 cytokine family that has been shown to play an important role in the induction and effector phases of type 2 immune responses. Both innate and adaptive i...

1 dig(s) Dig it Bury Topic: Immunology

The otherness of self: microchimerism in health and disease

submitted by cvigo 1 day ago

Microchimerism (Mc) refers to the harboring of a small number of cells (or DNA) that originated in a different individual. Naturally acquired Mc derives primarily from maternal cells in her progeny...

1 dig(s) Dig it Bury Topic: Immunology

Multimodality imaging and the emerging role of cardiac magnetic resonance in autoimmune myocarditis

submitted by JudahMaxim 1 day ago

Autoimmune responses and inflammation are involved in the excess cardiovascular risk observed in patients with systemic inflammatory diseases. Autoimmune myocarditis is a presentation of an inflamm...

1 dig(s) Dig it Bury Topic: Immunology

“Monovalent” ligands that trigger TLR-4 and TCR are not necessarily truly monovalent

submitted by arbioatefal18 1 day ago

Cell surface receptors mediate many cellular responses in health and disease. Recent progress in our understanding of how ligand binding to the extracellular domains of receptors triggers intracell...

1 dig(s) Dig it Bury Topic: Immunology