Gastroenterology

Successful treatment of refractory gastric antral vascular ectasia using transcatheter arterial embolization
In January 2008, a 67-year-old woman was admitted to our hospital because of hepatitis C virus-related cirrhosis and hepatocellular carcinoma (HCC). In February 2010, she had tarry stools and anemia resulting from gastric antral vascular ectasia (GAVE). Argon plasma coagulation (APC) treatment fo...


Neuropeptide Y inhibits biliary hyperplasia of cholestatic rats by paracrine and autocrine mechanisms
Neuropeptide Y (NPY) exerts its functions through six subtypes of receptors (Y1-Y6). Biliary homeostasis is regulated by several factors through autocrine/paracrine signaling. NPY inhibits cholangiocarcinoma growth, however, no information exists regarding the autocrine/paracrine role of NPY on b...
Translational Aspects of Rectal Evoked Potentials: A Comparative Study in Rats and Humans
Inconsistencies between species has stunted the progress of developing new analgesics. To increase the success of translating results between species, improved comparable models are required. Twelve rats received rectal balloon distensions on two different days separated by 24.3 (SD 24.6) days. R...
Degenerative Veränderungen der Wirbelsäule
Unspezifischer Rückenschmerz ist ein häufiges Phänomen. Bildgebende Verfahren zeigen häufig keine eindeutige Ursache für die Genese von Rückenschmerzen auf und haben in der Regel keine Auswirkungen auf das therapeutische Prozedere. Dagegen sind spezifische Rückenschmerzen, bei denen eine m...
Autophagy enhances hepatocellular carcinoma progression by activation of mitochondrial β-oxidation
Several types of cancers, including hepatocellular carcinoma (HCC), show resistance to hypoxia and nutrient starvation. Autophagy is a means of providing macromolecules for energy generation under such stressed-conditions. The aim of this study was to clarify the role of autophagy in HCC developm...
Comparative yield of fine needle aspiration cytology, ampullary biopsy, and needle knife assisted biopsy in the diagnosis of nonulcerated periampullary tumors
Periampullary tumors (PAT) are defined as tumors arising within 2 cm of the major duodenal papilla. Studies on yield of preoperative biopsy for nonulcerated PAT are scarce. Needle knife papillotomy-assisted biopsy (NKAB) may sample the deeper tissues and thereby increase the histologic yield. We...


Serum lactonase and arylesterase activities in alcoholic hepatitis and hepatitis B
PON1 is an HDL-associated enzyme having antioxidant activity. PON1 is synthesized in the liver, and there is decreased synthesis of PON1 with increased lipid peroxidation. The study was carried with the aim of establishing whether chronic liver disease (CLD) produced any significant changes in se...
Colonoscopic findings and management of patients with outbreak typhoid fever presenting with lower gastrointestinal bleeding
Lower gastrointestinal bleeding (LGIB) along with intestinal perforation is a well-known complication of typhoid fever. Reports of colonoscopic appearance and intervention of typhoid perforation involve only few cases. This series reports the colonoscopic findings and the role of colonoscopic hem...
Self Expandable Metal Stents for Anastomotic Stricture Following Liver Transplant
Endoscopic treatment for biliary strictures with plastic stent placement has been used widely. The use of covered self-expandable metal stents (CSEMS) has been reported in anastomotic strictures post liver transplant. The aim of this study was to evaluate the efficacy of different CSEMS in these ...
Long-Term Follow Up Reveals Low Incidence of Colorectal Cancer, but Frequent Need for Resection, Among Australian Patients with Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) can require surgical resection and also lead to colorectal cancer (CRC). We investigated the cumulative incidence of resection surgeries and CRC among patients with ulcerative colitis (UC) or Crohn’s disease (CD). We analyzed data from a cohort of patients who p...
Interpretation and Management of Hepatic Abnormalities in Pregnancy
The spectrum of liver disease in pregnancy includes liver disease unrelated to pregnancy, those that occur with increased frequency or severity in pregnancy and liver disease specific to pregnancy. Diseases of the liver unique to pregnancy reliably occur at specific points in the gestational spec...


Dietary Cholesterol Intake is Associated with Progression of Liver Disease in Patients With Chronic Hepatitis C: Analysis of the HALT-C trial
Little is known about whether dietary cholesterol affects disease progression in patients with chronic hepatitis C virus (HCV) infection. We analyzed data from the Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) trial, which included patients with advanced fibrosis and compen...
A case report: endoscopic enucleation of gastrointestinal stromal tumor of the ampulla of Vater
To report a case of endoscopic enucleation of a gastrointestinal stromal tumor of the ampulla of Vater.The tumor resection was performed by needle knife endoscopic submucosal dissection.The tumor was resected completely without serious complications and the patient recovered rapidly.Endoscopic en...
Detection of Neoplastic Gastric Lesions Using Capsule Endoscopy: Pilot Study
Endoscopy is relatively noninvasive method and its use extends from the small bowel to the esophagus and colon. The aim of this study was to evaluate the feasibility and acceptability of capsule endoscopy for neoplastic gastric lesions. Methods. Capsule endoscopy (Pillcam ESO) was performed withi...
Hepatic steatosis and severity-related factors in obese children
Obesity is an important healthcare problem in developed countries. It is considered a multi-systemic disease, but it may also affect the liver, thus provoking Nonalcoholic Fatty Liver Disease (NAFLD). This disease has been less extensively studied among children than among adults. We propose to a...