Dermatology

Concentrations and stability of methyl methacrylate, glutaraldehyde, formaldehyde and nickel sulfate in commercial patch test allergen preparations
Epicutaneous patch tests are used to reproduce allergy and diagnose allergic contact dermatitis. Reliable allergen test preparations are required. The purpose of the present study was to measure the actual concentrations of nickel(II) sulfate hexahydrate (NiSO4), methyl methacrylate, formaldehyde, and glutaraldehyde, and to compare them with the labelled concentrations, in commercial patch test...


Reaction profile in patch testing with allergens formed during vulcanization of rubber
Vulcanization of rubber changes its allergen pattern. To estimate the contact allergic reactivity profile of users of finished rubber products. Twenty-four patients with known contact allergy to rubber accelerators were patch tested with 21 compounds found in chemical analyses of vulcanized rubber products. No diphenylguanidine, p-phenylenediamine antioxidants or thioureas were included in the ...
Influence of Smoking on Wound Healing in Patients Undergoing Nail Matrix Phenolization: A Prospective Randomized Clinical Study
To enhance the learner’s competence with knowledge of the effect of smoking on wound healing in patients undergoing nail matrix phenolization. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. After participating in this educational activity, the participant should be better able to:Summarize factors that affect w...


Clinical and Microbiologic Evaluation of Chronic Leg Ulcers: A Cross-sectional Study
This study aimed at evaluating the flora and bacterial load of chronic leg ulcers (CLUs) according to the clinical judgment of colonization or infection. :This was an analytical and cross-sectional study. SEING:This study was conducted in an outpatient wound care unit in the Dermatology Department of the Botucatu School of Medicine–UNESP, Brazil. PARTICIPANTS:The participants were patients wi...
Effects of Paroxetine on Cutaneous Wound Healing in Healthy and Diabetic Rats
The aim of this study was to evaluate the histologic effects of acute paroxetine administration on wound healing in healthy and streptozotocin-induced diabetic rats. :This study has a randomized controlled experimental design. SEING:Healthy (n = 32) and diabetic (n = 32) rats were further divided into 2 groups of saline or paroxetine administration. PARTICIPANTS:Sixty-four male Sprague-Dawley r...


Clinical Evaluation Comparing the Efficacy of Aquacel Ag with Vaseline Gauze versus 1% Silver Sulfadiazine Cream in Toxic Epidermal Necrolysis
The purpose of this study was to determine whether using Aquacel Ag (ConvaTec, Skillman, New Jersey) with Vaseline (Unilever, London, England) gauze instead of silver sulfadiazine cream (SSD) as the wound care protocol to treat toxic epidermal necrolysis (TEN) can improve wound healing, pain control, and reduction of labor costs. :A retrospective chart review. SEING:A burn center with 2 plastic...
The Management of Intractable Pain with Adjuvant Pulsed Electromagnetic Field Therapy
This case describes a 51-year-old woman who reported experiencing severe, constant pain, diffusely located in the region of her right mandible neck (primarily involving the mandible, lower right molars, the neck, the upper back, and the shoulder) during the course of several years. Surgical interventions (root canal, spinal fusion) were performed to address potential sources of pain. Despite th...

Expression dynamics of CXCL12 and CXCR4 during the progression of mycosis fungoides
Mycosis fungoides (MF) classically presents from patch stage to plaque stage over a number of years and finally progresses to tumour stage with nodal or visceral involvement and the mechanism of progression remains incompletely elucidated. Whereas, chemokines and their receptors have been shown as clues for disease mechanisms, CXCL12 and CXCR4 play a critical role in carcinogenesis, invasion, a...
Systemic corticosteroids for subcutaneous panniculitis-like T-cell lymphoma
Primary cutaneous γ/δ T cell lymphoma (PCGD-TCL) is aggressive, and with poor prognosis. In contrast, subcutaneous panniculitis-like T cell lymphoma (SPTCL) of α/β T cell receptor phenotype has been understood to follow an indolent course and have a more favorable prognosis. In the past, PCGD-TCL and SPTCL were often considered to be a manifestation of the same disease and aggressive system...

Lifting the Veil off Reporting Evaluation and Management Services on the Same Date of Service as a Procedure
The Centers for Medicare and Medicaid Services added enhanced narrative under the Integumentary section of the National Correct Coding Initiative code edits that affect the reporting of an evaluation and management (E/M) service on the date of service (DOS) as a procedure. Although the enhanced narrative indicates that an E/M service is included in the minor procedure when reported on the same ...
Acne Research: Are We Answering the Right Questions?
Acne is one of the most common dermatological conditions affecting millions of people worldwide. Although often considered a disease of young people, it is increasingly seen in adults, especially adult women. Acne can cause significant physical and psychological suffering, and yet, there is relatively little research into causes and treatments. Increasing importance is being attached to patient...

From Sun Addicted to Sun Savvy: Melanoma From a Patient’s Perspective
Diagnosed with melanoma at the age of 19 years, I’ve learned the importance of finding healthcare professionals who make you feel at ease and who take time out to answer your many questions. I now see a diagnosis as a wake-up call to action, as diet and lifestyle factors play an important role in the prevention and development of disease. This is my story, which I am sharing to allow others, ...
Sunscreens
The purpose of this article is to present a brief overview on sunscreen and is not intended to be a full review. Statistical information on skin cancer is presented along with an overview of skin protective measures in addition to sunscreen. A brief description of the definition of ultraviolet (UV) radiation is reviewed and includes the basic differences between UVA and UVB. Chemical blockers v...
Current Behaviors, Attitudes, and Knowledge of Nurse Practitioners in Primary Care Toward Skin Cancer Screening/Prevention
The purpose of this study was to better understand what behaviors, attitudes, and knowledge nurse practitioners (NPs) working in primary care have on the topic of skin cancer screening and prevention. Skin cancer is currently the most commonly diagnosed cancer in the United States, and the prevalence of skin cancer diagnoses continues to rise. Currently, melanoma stands alone as the most common...
Terapia fotodinámica con luz de día en España: ventajas y limitaciones
La terapia fotodinámica (TFD) constituye una alternativa terapéutica para las queratosis actínicas, la enfermedad de Bowen y determinados carcinomas basocelulares. Se utiliza además para el tratamiento de otras enfermedades cutáneas de diversa naturaleza, incluyendo enfermedades inflamatorias e infecciosas. Los principales inconvenientes de la TDF convencional son el tiempo que consume su ...