Dentistry

Enhanced M1/M2 Macrophage Ratio Promotes Orthodontic Root Resorption
Mechanical force–induced orthodontic root resorption is a major clinical challenge in orthodontic treatment. Macrophages play an important role in orthodontic root resorption, but the underlying mechanism remains unclear. In this study, we examined the mechanism by which the ratio of M1 to M2 macrophage polarization affects root resorption during orthodontic tooth movement. Root resorptio...


The Interplay between Socioeconomic Inequalities and Clinical Oral Health
Oral health inequalities associated with socioeconomic status are widely observed but may depend on the way that both oral health and socioeconomic status are measured. Our aim was to investigate inequalities using diverse indicators of oral health and 4 socioeconomic determinants, in the context of age and cohort. Multiple linear or logistic regressions were estimated for 7 oral health measure...
Resin-composite Blocks for Dental CAD/CAM Applications
Advances in digital impression technology and manufacturing processes have led to a dramatic paradigm shift in dentistry and to the widespread use of computer-aided design/computer-aided manufacturing (CAD/CAM) in the fabrication of indirect dental restorations. Research and development in materials suitable for CAD/CAM applications are currently the most active field in dental materials. Two c...


Impact of oral mucositis on oral-health-related quality of life of patients diagnosed with cancer
Oral mucositis (OM) has been described as the oral complication most frequently associated with antineoplastic therapy. However, the influence on the quality of life of affected patients is still unclear. To evaluate the impact of OM on the oral-health-related quality of life (OHRQoL) of patients diagnosed with cancer, who developed chemotherapy- and/or radiotherapy-induced OM. This is a cross-...
The Shortened Dental Arch Concept: Awareness and opinion of dentists in Victoria, Australia
The occlusion of a complete dental arch is generally desirable but not necessary nor always achievable in many individuals. It is, however, relevant for dentists to consider what minimum number of teeth is required by individuals for oral function. This study investigated dentists’ awareness and opinion of the shortened dental arch (SDA) concept in an Australian context. A self-administered v...


Patient perspectives of diagnostic delay for suspicious oral mucosal lesions
This study aimed to investigate patient experiences regarding the discovery of and subsequent referral for suspicious oral mucosal pathology. The population under investigation were patients of an oral medicine clinic in Australia who had been referred for oral lesions suspected for malignancy. A self-completed questionnaire gathered information regarding patient experiences and beliefs leading...
Possible implications of Ni(II) on oral IL-1β-induced inflammatory processes
Nickel (Ni) is one of the main metal elements in orthodontic and prosthetic devices. Different effects of Ni are described ranging from an induction of local inflammation to allergy and cancerous/mutagenic properties. Inflammatory reactions are frequently observed in the oral cavity, but the interrelationship of Ni with those events is still unknown. Therefore, we focused on the impact of Ni on...

Dental materials for primary dentition: are they suitable for occlusal restorations? A two-body wear study
This was to evaluate the wear resistance of different materials, compomers, resin-modified glass ionomer cements (RMGICs), glass ionomer cements (GICs), used for posterior restorations in primary teeth and to compare the results with the reference material, amalgam. Eight specimens of each material were subjected to two-body wear test, using a chewing simulator. The wear region of each material...
A retrospective analysis of caries treatment and development in relation to assessed caries risk in an adult population in Sweden
The Public Dental Service of Västerbotten County (Sweden) recommends using population-based prevention strategies combined with an individual strategy for high-risk patients to manage caries. To facilitate this management strategy, all patients are evaluated for their risk of developing caries in the coming year using defined criteria. Using caries risk scoring over a seven-year period, the pr...

Prevalence and correlates of dental anxiety in patients seeking dental care
To examine the prevalence of dental anxiety and its associations with pain and other psychological variables among patients seeking dental treatment and develop a directed acyclical graph of these relationships. One hundred and twenty patients who sought regular or emergency dental care completed a semi-structured interview assessing DSM-IV specific phobia of dental procedures and questionnaire...
Factors related to the willingness of Palestinian dentists to treat patients with blood-borne diseases
This study aimed to explore, using groups of simulated patients, the willingness of Palestinian dentists to treat patients with blood-borne diseases. Simulated patients conducted a telephone survey of a random sample of dentists registered with the Palestinian Dental Association. A random system was used to assign dentists to one of two groups, in which simulated patients randomly identified th...

HIV/AIDS: dental assistants' self-reported knowledge and attitudes in Kuwait
Although several studies have been conducted to assess dentists' knowledge of and attitudes towards human immunodeficiency virus (HIV)/acquired immune-deficiency syndrome (AIDS), few have targeted dental assistants. The main aims of this study were to assess the knowledge of and attitudes towards HIV/AIDS among dental assistants in Kuwait and to compare the knowledge and attitudes of dental ass...
Toll-like receptor 9 mediates invasion and predicts prognosis in squamous cell carcinoma of the mobile tongue
Toll-like receptor 9 (TLR9) is a cellular receptor, which recognizes bacterial and host-derived DNA. Stimulation of TLR9 induces cellular invasion via matrix metalloproteinase 13 (MMP-13). The aim of this study was to evaluate the role of TLR9 in invasion of oral tongue squamous cell carcinoma (OTSCC). The effects of TLR9 ligands on oral squamous cell carcinoma cell lines were studied with inva...
Comparison of fixed implant-supported prostheses, removable implant-supported prostheses, and complete dentures: patient satisfaction and oral health-related quality of life
The purpose of this study was to compare patient satisfaction and oral health-related quality of life (OHRQoL) among fully edentulous patients treated with either fixed implant-supported prostheses (FP), removable implant-supported prostheses (RP), or complete dentures (CD). Material and MethodsEighty-six patients – 29 FP, 27 RP, and 30 CD patients – participated in this study. The survey w...
Metatranscriptomics reveals overall active bacterial composition in caries lesions
: Identifying the microbial species in caries lesions is instrumental to determine the etiology of dental caries. However, a significant proportion of bacteria in carious lesions have not been cultured, and the use of molecular methods has been limited to DNA-based approaches, which detect both active and inactive or dead microorganisms.: To identify the RNA-based, metabolically active bacteria...