Chemical Engineering

Protein attachment to nanoporous anodic alumina for biotechnological applications: Influence of pore size, protein size and functionalization path
Nanoporous anodic alumina (NAA) is a material with great interest in nanotechnology and with promising applications to biotechnology. Obtaining specific and regularly functionalized NAA surfaces is essential to obtain meaningful results and applications. Silane-PEG-NHS (triethoxysilane-polyethylene-glycol-N-hydroxysuccinimide) is a covalent linker commonly used for single-molecule studies. We i...


Impact of electrolytes on double emulsion systems (W/O/W) stabilized by an amphiphilic block copolymer
In this work, the block copolypeptide surfactant, poly(l-lysine·HBr)40-b-poly(racemic-leucine)20, was synthesized and characterized, then used to build water-in-oil-in-water (W/O/W) double emulsions. Double emulsions are usually prepared by a two-step emulsification process and commonly stabilized using a combination of hydrophilic and hydrophobic surfactants. Herein, we report a one-step phas...
Enhanced osteogenesis of bone morphology protein-2 in 2-N,6-O-sulfated chitosan immobilized PLGA scaffolds
By using 2-N,6-O-sulfated chitosan (26SCS) immobilized poly(lactide-co-glycolide) (PLGA) scaffolds, our system achieved controlled release and improved bioactivity of recombinant human bone morphology protein-2 (rhBMP-2). Initially aminolyzed by ethylenediamine, PLGA scaffolds surface was immobilized with 26SCS via electrostatic assembly. Upon the presence of 26SCS, the system displayed improve...


Cis-Dichlorodiamminoplatinum (II) glyconanoparticles by drug-induced ionic gelation technique targeted to prostate cancer: Preparation, optimization and in vitro characterization
Cancer stem cells (CSC) have been proposed as the reason of cancer relapse which are characterized mainly based on CD44+ phenotype with other supplementary markers. The aim of the present study is to fabricate cis-dichlorodiamminoplatinum (II) (CDDP) loaded glyconanoparticles using hyaluronic acid (HA) which is also known as the endogenous substrate for CD44 in vivo. For this purpose, a drug-in...
A new approach for the delivery of artemisinin: Formulation, characterization, and ex-vivo antileishmanial studies
Artemisinin, a potential antileishmanial compound with poor bioavailability and stability has limited efficacy in visceral leishmaniasis. Encapsulating artemisinin into poly lactic-co glycolic nanoparticles may improve its effectiveness and reduce toxicity. Artemisinin-loaded nanoparticles were prepared, optimized (using Box–Behnken design) and characterized by dynamic light scattering techni...


In vitro evaluation of graphene oxide nanosheets on immune function
Graphene oxide (GO) has attracted the scientific community attention due to its novel properties and wide range of potential applications including hyperthermia cancer therapy. However, little is known about the GO effects on the immune function which involves both innate and adaptive defence mechanisms through the activation of different cell populations and secretion of several cytokines. The...
Conditioning materials with biomacromolecules: Composition of the adlayer and influence on cleanability
The influence of substrate hydrophobicity and biomacromolecules (dextran, bovine serum albumin – BSA) adsorption on the cleanability of surfaces soiled by spraying aqueous suspensions of quartz particles (10–30μm size), then dried, was investigated using glass and polystyrene as substrates. The cleanability was evaluated using radial flow cell (RFC). The surface composition was determined ...

Influence of mineral characteristics on the retention of low molecular weight organic compounds: A batch sorption–desorption and ATR-FTIR study
Batch experiments were conducted to evaluate the sorption–desorption behaviour of 14C-labelled carboxylic acids (citric and oxalic) and amino acids (glutamic, alanine, phenylalanine and lysine) on pure minerals (kaolinite, illite, montmorillonite, ferrihydrite and goethite). The sorption experiments were complemented by ATR-FTIR spectroscopy to gain possible mechanistic insight into the organ...
Selective hydrogenation of o-chloronitrobenzene over anatase-ferric oxides supported Ir nanocomposite catalyst
The catalytic performance of Ir/TiO2–FeO x , an Ir/TiO2 catalyst modified with FeO x , was investigated for the hydrogenation of o-chloronitrobenzene, FeO x was found to promote both the activity and selectivity significantly. The initial reaction rate of Ir/TiO2–FeO x nanocomposite catalyst was four times as high as that of Ir/TiO2 catalyst. Especially, the accumulation of intermediates ...

Zinc Oxide nanorod/Au composite arrays and their enhanced photocatalytic properties
In this paper, a high-performance photocatalyst of ZnO nanorod/Au composite arrays (ZAs) was synthesized via a facile low-temperature wet chemical method. The samples were characterized using field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS), photoluminescence (PL) emission spectroscopy and ultraviolet–visib...
Adsorption of a cationic surfactant by a magsorbent based on magnetic alginate beads
Adsorption of cetylpyridinium chloride (CPC), a cationic surfactant, by magnetic alginate beads (MagAlgbeads) was investigated. The magnetic adsorbent (called magsorbent) was prepared by encapsulation of magnetic functionalized nanoparticles in an alginate gel. The influence on CPC adsorption of several parameters such as contact time, pH and initial surfactant concentration was studied. The eq...

Influence of ionic strength on the surface charge and interaction of layered silicate particles
The surface charge densities and surface potentials of selected phyllosilicate surfaces were calculated from AFM surface force measurements and reported as a function of ionic strength at pH 5.6. The results show that the silica faces of clay minerals follow the constant surface charge model because of isomorphous substitution in the silica tetrahedral layer. A decreasing surface charge density...
Layer-by-layer assembled films of multi-walled carbon nanotubes with chitosan and cellulose nanocrystals
Chitosan solutions and cellulose nanocrystal suspensions were used to produce highly stable aqueous dispersions of multi-walled carbon nanotubes (MWCNTs). The different MWCNT dispersions, presenting positive and negative charges, were used to prepare multilayered hybrid thin films through electrostatic layer-by-layer (LBL) self-assembly. The MWCNTs are well dispersed and homogeneously distribut...
Influences of structural mismatch on morphology, phase transition temperature, segmental dynamics and color-transition behaviors of polydiacetylene vesicles
In this contribution, we report a systematic study of polydiacetylene (PDA) vesicles fabricated by mixing two types of monomers, 10,12-tricosadiynoic acid (TCDA) and 10,12-pentacosadiynoic acid (PCDA). These diacetylene (DA) monomers constitute the same head group but different alkyl chain length, which in turn causes structural mismatch within the PDA layers. The PCDA:TCDA ratios are 100, 75, ...
The synergistic effect of the combined thin multi-walled carbon nanotubes and reduced graphene oxides on photothermally actuated shape memory polyurethane composites
We evaluated the synergistic effect of the hybrid-type nanocarbon, consisting of 1D thin-walled carbon nanotubes (TWNTs) and 2D reduced graphene oxide (RGO), on the shape memory performance of hyperbranched polyurethane composites. The shape recovery of the resulting composites was activated via a photothermal process using a near-infrared laser. The best laser-induced shape recovery performanc...