Organics

Phase Behavior of Glycerol Trioleate-Based Ionic Liquid Microemulsions
Glycerol trioleate-based ionic liquid microemulsions are promising biolubricant alternatives. This study presents the formation and the phase behavior of glycerol trioleate-based ionic liquid microemulsions. Areas of the single-phase domain were calculated to illustrate the phase-forming capacities of the designed systems. The effects of ionic liquid anions and cations, oxyethylene groups’ nu...


Multistage growth of Fe–Mg–carpholite and Fe–Mg–chloritoid, from field evidence to thermodynamic modelling
We provide new insights into the prograde evolution of HP/LT metasedimentary rocks on the basis of detailed petrologic examination, element-partitioning analysis, and thermodynamic modelling of well-preserved Fe–Mg–carpholite- and Fe–Mg–chloritoid-bearing rocks from the Afyon Zone (Anatolia). We document continuous and discontinuous compositional (ferromagnesian substitution) zoning of ...
Assessing the origin of old apparent ages derived by Pb stepwise leaching of vein-hosted epidote from Mount Isa, northwest Queensland, Australia
Epidote metasomatism affected large areas of tholeiitic metabasalts of the ~1,780 Ma Eastern Creek Volcanics in the Western Fold Belt of the Proterozoic Mount Isa inlier. Hydrothermal epidote generally occurs in quartz veins parallel to or boudinaged within the dominant S2 fabrics which formed during the regional metamorphic peak at ~1,570 Ma associated with the Isan orogeny. Previously publi...


Settling and compaction of chromite cumulates employing a centrifuging piston cylinder and application to layered mafic intrusions
The time scales and mechanics of gravitationally driven crystal settling and compaction is investigated through high temperature (1,280–1,500 °C) centrifuge-assisted experiments on a chromite-basalt melt system at 100–1,500g (0.5 GPa). Subsequently, the feasibility of this process for the formation of dense chromite cumulate layers in large layered mafic intrusions (LMIs) is assessed. Cen...
Controls on solid-phase inclusion during porphyroblast growth: insights from the Barrovian sequence (Scottish Dalradian)
A series of Barrovian sequence samples ranging from garnet to sillimanite zones were investigated to infer their porphyroblast-forming reactions and mineral inclusion histories. Quartz is overgrown and partly consumed during garnet formation and remains as inclusion-rich layers in porphyroblasts of the garnet zone. Staurolite crystals in the staurolite zone display sharp transitions between inc...


The age of Au–Cu–Pb-bearing veins in the poly-orogenic Ubendian Belt (Tanzania): U–Th–total Pb dating of hydrothermally altered monazite
The age of gold–copper–lead mineralization in the Katuma Block of the Ubendian Belt remains controversial because of the lack of radiometric ages that correlate with the age of tectonothermal events of this poly-orogenic belt. Previous studies reported whole rock and mineral Pb–Pb ages ranging between 1,660 and 720 Ma. In this study, we report U–Th–total Pb ages of monazite from hydr...
Preparation of Multivalent Carbohydrate Mimetics Based on Enantiopure 1,2-Oxazines by Sonogashira Coupling and Subsequent Reductive Ring-Opening
A modular approach to aryl C-glycosides and their multivalent analogues is presented. Sonogashira coupling reactions connected the key compounds, enantiopure bicyclic 1,2-oxazine derivatives bearing p-bromophenyl substituents, with alkynes. Subsequent hydrogenolyses or a combination of hydrogenolysis and samarium diiodide mediated reductions converted the coupling products into new unnatural am...

Ligand- and Base-Free CuII-Mediated Selective S-Arylation of α-Enolic Dithioesters by Chan–Lam Coupling at Room Temperature
The ligand- and base-free copper(II)-mediated Chan–Lam cross-coupling of arylboronic acids with α-enolic dithioesters has been achieved at room temperature under aerobic neutral conditions to afford unsymmetrical α-oxoketene S,S-acetals for the first time. This operationally simple, mild protocol tolerates a wide range of arylboronic acids and α-enolic dithioesters. Typical features of thi...
Superstable Palladium(0) Complex as an Air- and Thermostable Catalyst for Suzuki Coupling Reactions
An unprecedentedly thermo- and air-stable Pd0 complex from readily available electron-poor trifluoromethylated phosphine was serendipitously discovered. As detailed and comparative DFT calculations indicate, the stability of the complex is associated with unusually strong ligand–ligand noncovalent interactions. The unique stability and the presence of hydrophobic structural elements of the co...

Dibenzoporphycene – Platform for the Generation of Fused Porphycenes
Fused porphycenes have attracted growing interest in recent years. However, the molecules generated to date suffer from different drawbacks such as multistep syntheses, low yields, and the lack of a convenient synthetic strategy. Here, we present our latest results concerning the synthesis of a suitable platform for the generation of large fused porphycenes. A fused porphycene is generated thro...
Pentaerythritol-Based Energetic Materials Related to PETN
New tetravalent pentaerythritol tetranitrocarbamate (PETNC) and its tetraammonium salt have been synthesized by an efficient two-step synthesis starting from the cheap and commercially available pentaerythritol. In addition to full spectroscopic characterization, their thermal stabilities were examined by differential thermal analysis, and their energies of formation calculated. Furthermore, th...

Comparative phosphoproteomic analysis of mammalian glomeruli reveals conserved podocin C-terminal phosphorylation as a determinant of slit diaphragm complex architecture
Glomerular biology is dependent on tightly controlled signal transduction networks that control phosphorylation of signaling proteins such as cytoskeletal regulators or slit diaphragm proteins of kidney podocytes. Cross-species comparison of phosphorylation events is a powerful mean to functionally prioritize and identify physiologically meaningful phosphorylation sites. Here, we present the re...
A web-tool for visualizing quantitative protein-protein interaction data
Quantitative interaction proteomics data can be a challenge to efficiently analyze and subsequently present to an audience in a simple and easy to understand format that still conveys sufficient levels of information. Here we present freely-accessible and open-source web tools for displaying multiple parameters from quantitative protein-protein interaction data sets in a visually intuitive form...
JSparklines: Making tabular proteomics data come alive
Perhaps the most common way of presenting proteomics data, and indeed life sciences data in general, is by using some form of tabular data. And while tables can be very informative and contain lots of information, the format can be challenging to interpret visually. An elegant and efficient solution is to extend the textual and numerical information with an additional visual layer, referred to ...
Identification of prolyl hydroxylation modifications in mammalian cell proteins
Prolyl hydroxylation is a post-translational modification (PTM) that plays an important role in the formation of collagen fibrils and in the oxygen-dependent regulation of Hypoxia Inducible Factor-α (HIF-α). While this modification has been well characterized in the context of these proteins, it remains unclear to what extent it occurs in the remaining mammalian proteome. We explored this que...