submitted by cvigo 1 hour ago
Healthy skeletal muscle has a remarkable capacity for regeneration. Even at a mature age, muscle tissue can undergo a robust rebuilding process that involves the formation of new muscle cells and extracellular matrix and the re-establishment of vascular and neural networks. Understanding and reve...
submitted by AlleDenni 6 hours ago
Phytochemical investigation of the aerial parts of Euphorbia sikkimensis led to the isolation of one new diterpenoids, named sikkimenoid E (1), together with thirteen other known compounds (2–14). Their structures were established by means of spectroscopic methods. Compound 2 was identified to ...
submitted by deono2119 8 hours ago
Bisphenol A (BPA) and 4-n-nonylphenol (4-n-NP) present significant research interests due to their extensive use and toxicological properties. Batch experiments were conducted to investigate the sorption and degradation behavior of BPA and 4-n-NP using acclimated activated sludge either under ano...
submitted by DavAide 11 hours ago
Mitochondrial outer membrane permeabilization (MOMP) is a crucial step leading to apoptotic destruction of cancer cells. Bcl-2 family proteins delicately regulate mitochondrial outer membrane integrity through protein-protein interactions, which makes the mitochondrion an ideal cell-free system f...
submitted by soltcidor 15 hours ago
In this work a defined co-culture of the lactic acid bacterium Lactobacillus zeae and the propionate producer Veillonella criceti has been studied in chemostat and in a dialysis membrane reactor. It is the first time that this reactor type is used for a defined co-culture fermentation. This react...
submitted by ConBre 23 hours ago
Chinese hamster ovary (CHO) cells producing β-galactosidase (β-gal) were successfully cultured on silicone-based porous microcarriers (ImmobaSil FS) in a 1 L stirred-tank perfusion bioreactor. We studied the growth, metabolism, and productivity of free and immobilized cells to understand cellu...
submitted by ono 1 day ago
Proteases play critical roles in numerous physiological processes and thus represent one of the largest families of potential pharmaceutical targets. Previous failure of broad-spectrum small molecule inhibitors toward tumorigenic metalloproteinases in clinical trials emphasizes that selectivity i...
submitted by ermo 1 day ago
Erlenmeyer flask or conical flask, usually made of glass, is widely used for laboratory scale suspension culture of microorganism, such as Escherichia Coli and yeast. Due to being non-disposable culture vessel, it has to be cleaned, packaged and sterilized prior to use, which are time, labor and ...
submitted by iqaiscaal 1 day ago
Oil-rich algae are potentially promising as next-generation biofuel feedstock. However, the productivity of oil needs to be improved for industrial use. The biosynthesis of oil and its control mechanism have not been characterized in any algae, and understanding the metabolic network is vital to ...
submitted by forhod 2 days ago
The effect of the B cation on the surface properties and catalytic activity in the dry reforming reaction over La0.4M0.6Al0.2Ni0.8O3 (M = Noble Metals) perovskite-type oxides with surface areas of 3.26–4.14 m2/g and rhombohedra structures was studied. Among LaAlxNi1-xO3 series, the LaAl0....
submitted by oleanomarorea 2 days ago
Whereas multi-species biofilm reactors are commonly used for the treatment of liquid and solid wastes, new strategies are progressively arising for the development of single species biofilm for the production of high-value metabolites. Technically, this new concept relies on the design of bioreac...
submitted by MavEme 2 days ago
Biofuel crops are promoted as a climate friendly alternative to fossil energy. Yet environmental risks such as potential biodiversity loss are not always adequately considered. This might occur directly as a consequence of land-use change from natural systems to biofuel plantations, but also thro...
submitted by felixsch4 2 days ago
Despite their rigidity, microtubules in living cells bend significantly during polymerization resulting in greater curvature than can be explained by thermal forces alone. However, the source of the non-thermal forces that bend growing microtubules remains obscure. We analyzed the motion of micro...
submitted by vohed2345 2 days ago
The underglycosylated form of the MUC1 glycoprotein, uMUC1, has been identified as a ligand for both E-selectin and ICAM-1 and can play multiple potential roles during rolling and firm adhesion events in the metastatic cascade. Using flow cytometry and confocal microscopy, the T47D and ZR-75-1 ce...
submitted by TerreRees 2 days ago
Poly[R-3-hydroxybutyrate-co-(R-3-hydroxyvalerate)] (PHBV) copolymers were produced from mixed cultures of biomass (activated sludge) fed with acetic and propionic acids. Feeding was performed in such a way as to produce materials with a wide range of monomer compositions and microstructures. Solv...