The Phytochemical, Elemental and Hematologic Evaluation of Crude Mesocarp Extract of Hyphaene thebaica (doumpalm) in Wistar Albino Rats
submitted by leno6691 10 months ago - Topic: Biochemistry
Protective Effect of Smilax zeylanica L. Leaf against Paracetamol Induced Hepatic Damage in Wistar Rats
submitted by WadEzekiel 1 year and 5 months ago
Hepatoprotective properties of the methanol extract of the leaf of Smilax zeylanica was evaluated on paracetamol induced hepatotoxicity in Wistar rats. Hepatotoxicity was induced in albino Wistar rats by the administration of paracetamol (1g/kg), p.o. for seven days. Methanol extract of leaf of S...
Hepatoprotective Effect of Ethyl Acetate Extract of Vitex doniana Stem Bark on Carbon Tetrachloride (CCl4) Induced Liver Damage in Wistar Rats
submitted by jsdadsan 1 month ago
The hepatoprotective effect of Ethyl Acetate Extract of Vitex doniana (EAEVD) stem bark on carbon tetrachloride (CCl4) induced hepatic damage was studied, to evaluate some biochemical parameters, to determine the in vitro antioxidant effect of the extract on Superoxide Dismutase (SOD), Catalase (...
Evaluation of Mallotus oppositifolius Methanol Leaf Extract on the Glycaemia and Lipid Peroxidation in Alloxan-Induced Diabetic Rats: A Preliminary Study
submitted by SagePhil 6 months ago
Mallotus oppositifolius (Geiseler) Müll. Arg. (Euphorbiaceae) is folklorically used to “treat” diabetic conditions in some parts of Nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in ...
Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens
submitted by stiphinhjocabsan 1 year and 8 months ago
Oxidative stress and impaired antioxidant system have been implicated in the pathophysiology of diverse disease states. The phytochemical screening and antioxidant property of fresh leaves of Vitex doniana and Mucuna pruriens, used in the management and treatment of various diseases, were studied...
A rapid HPLC-ESI-MS/MS method for determination of β-asarone, a potential anti-epileptic agent, in plasma after oral administration of Acorus calamus extract to rats
submitted by JudahMaxim 1 year and 7 months ago
Β-Asarone (BAS), a phenylpropanoid from Acorus calamus Linn., has shown biological effects in the management of cognitive impairment conditions such as Alzheimer's disease. The present paper describes a selective and sensitive liquid chromatography–tandem mass spectrometric method (HPLC-MS/MS)...
Liver Protective Activity of the Methanol Extract of Crinum jagus Bulb against Acetaminophen-induced Hepatic Damage in Wistar Rats
submitted by lisabird 1 year and 6 months ago
Hepatotoxins constitute a serious health concern in both rural and urban population globally. Despite advances in medical research, the discovery of an ideal hepatoprotective agent remains a challenge. The present research sought to evaluate the hepatoprotective activity of the crude methanol ext...
submitted by hritargrxaac 5 months ago
Radiopharmaceuticals are localized in (malignant) tumor tissues by different mechanism. One of these mechanisms, the gelatinase enzymes is associated with poor prognosis in cancer patients and potential targets for tumor imaging. These are some gelatinase to be associated with metastatic potentia...
Β-Adrenoreceptor Agonist Isoproterenol Alters Oxidative Status, Inflammatory Signaling, Injury Markers and Apoptotic Cell Death in Myocardium of Rats
submitted by ZackePeter 2 months ago
Sustained high levels of circulating catecholamines are reported to induce cardiotoxicity. Isoproterenol (ISP), a synthetic catecholamine has been widely employed to induce myocardial injury, though the role of inflammation and apoptosis is not well established. This study was designed to investi...
submitted by hamdastoro 1 year and 1 month ago
Ulcerogenic and intestinal motility/transit stimulating actions of nevirapine in albino Wistar rats
submitted by Cristoba 10 months ago
Diabetes mellitus is one of the most common endocrine metabolic disorders. Dual endocrine deficits of impaired insulin action (insulin resistance) and inadequate insulin secretion create an environment of chronic hyperglycemia and general metabolic disarray. Oxidative stress plays an important ro...