Se presenta el caso de una mujer de 18 años con un cuadro de diarrea, dolor abdominal y ptosis palpebral izquierda. La resonancia nuclear magnética cerebral (RMN) y el estudio del líquido cefalorraquídeo fueron normales. La colonoscopia estableció el diagnóstico de enfermedad de Crohn (EC) confirmándose en el estudio histopatológico. La afectación ocular mejoró tras el adecuado tratamiento de la EC. La enfermedad inflamatoria intestinal (EII) se asocia a una amplia variedad de manifestaciones extraintestinales, de hecho puede ser considerada como una enfermedad sistémica que afecta predominantemente al tracto gastrointestinal. Las manifestaciones extraintestinales acontecen hasta en una tercera parte de los pacientes afectos de EII. Las complicaciones oculares son infrecuentes, afectando a menos del 10% de los casos, pero en ocasiones comportan una significativa morbilidad, incluyendo la ceguera. La sintomatología ocular puede preceder al diagnóstico de EII. Informamos el primer caso de ptosis palpebral asociado a EC. Clinical case An 18 year-old-woman presented with abdominal pain, diarrhea, and ptosis in her left eye. Nuclear magnetic resonance imaging (NMRI) and the study of cerebrospinal fluid detected no abnormalities. Colonoscopy revealed a Crohn's disease (CD) confirmed by histological examination of biopsies. Ocular symptoms improved after appropriate treatment of the underlying CD. Inflammatory bowel disease (IBD) is associated with a wide variety of extra-intestinal manifestations, in fact it may be considered a systemic disorder with predominantly gastrointestinal tract manifestations. Extra-intestinal manifestations of inflammatory bowel disease (IBD) occur in one third of patients. Ocular complications are infrequent, occurring in less than 10% of cases, but can be associated with significant morbidity, including blindness. Ocular symptoms may precede a diagnosis of IBD. We report the first case of palpebral ptosis associated with Crohn's disease.
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