Submit Story | Join | Login

 
View All Biology Business Chemistry Engineering Geography Health Mathematics Society
 





Development and validation of a novel tool to estimate peri-operative blood loss

submitted by andybohra 2 months ago


Surgical blood loss predicts peri-operative outcomes. We have developed and validated Blood Loss Scores to estimate peri-operative blood loss during major abdominal surgery. Surgical blood loss and changes in haemoglobin concentration were recorded intra- and postoperatively for 48 h in 100 patients undergoing radical prostatectomy. Data from the first group (n = 50) were used to derive the Blood Loss Scores which were validated against the data from a second group (n = 50) at three time points (immediately postoperative and 24- and 48-h later). The score, taking into account suction fluid volume and haemoglobin concentration, explained more of the variance in the measured blood loss than the experts’ assessment (77% vs 54%, p = 0.05) or the change in haemoglobin concentration (77% vs 11%, p < 0.0001). Addition of the change in haemoglobin concentration improved the estimate for the 24- and 48-h postoperative Blood Loss Scores to explain 78% and 80% of the variance of measured blood loss.

Topic: Immunology



Add your comment

Please Login or Signup to leave a comment


Related stories

Numerical Modeling of Anisotropic Fiber Bundle Behavior in Oxygenators
submitted by HoldVance 7 months ago
Prediction of flow patterns through oxygenator fiber bundles can allow shape optimization so that efficient gas exchange occurs with minimal thrombus formation and hemolysis. Computational fluid dynamics (CFD) simulations can be used to predict three-dimensional flow velocities and flow distribut...
 


A clinical prediction tool to estimate the number of units of red blood cells needed in primary elective coronary artery bypass surgery
submitted by jsdadsan 1 year and 11 months ago
Red blood cell (RBC) transfusion is common during cardiac surgical procedures. Empiric crossmatching, without attempting to estimate individual transfusion requirements is typical. We hypothesized that a clinical prediction tool could be developed to estimate the number of units of RBCs needed fo...
 
Peripheral and central arterial pressure and its relationship to vascular target organ damage in carotid artery, retina and arterial stiffness. Development and validation of a tool. The Vaso risk study
submitted by MasoBru 1 year and 1 month ago
Ambulatory blood pressure monitoring (ABPM) shows a better correlation to target organ damage and cardiovascular morbidity-mortality than office blood pressure. A loss of arterial elasticity and an increase in carotid artery intima-media thickness (IMT) has been associated with increased cardiova...
 
Comprehensive Analysis of Variables Affecting Delayed Gastric Emptying Following Pancreaticoduodenectomy
submitted by hononnsaar 1 month ago
Delayed gastric emptying (DGE) occurs commonly following pancreaticoduodenectomy (PD), and criteria for its clinical diagnosis have recently been standardized by an international consensus group. We evaluated 24 operative and peri-operative variables to assess which were independent risk factors ...
 
Acute kidney injury during liver transplantation as determined by neutrophil gelatinase-associated lipocalin
submitted by edihioran 2 years and 5 months ago
Acute kidney injury (AKI) has significant prognostic implications for long-term outcomes in patients undergoing liver transplantation. In several retrospective studies, perioperative variables have been associated with AKI. These variables have been mainly associated with changes in creatinine co...
 
Validation of soil organic carbon dynamics model in the semi-arid tropics in Niger, West Africa
submitted by sodighepaar 1 year and 7 months ago
The fertility of sandy soils in the Sahelian zone (SZ) is extremely low. This poor soil fertility is one of the limiting factors of crop production in the SZ. Therefore, it is imperative to improve or to maintain soil fertility through various agricultural management methods. Further, it is well ...
 
Development and validity of two-question screening test for depressive disorders in Northeastern Thai community
submitted by pmcovay3 2 years and 5 months ago
To develop a screening test for depressive disorders which is simple and short. To determine the diagnostic accuracy of this screening test in Northeastern Thai community.From August 2006 through October 2006, two phases of tool development were conducted. The first phase, a two-question screenin...
 
Modelling European winter wind storm losses in current and future climate
submitted by skaalva 2 years and 5 months ago
Severe wind storms are one of the major natural hazards in the extratropics and inflict substantial economic damages and even casualties. Insured storm-related losses depend on (i) the frequency, nature and dynamics of storms, (ii) the vulnerability of the values at risk, (iii) the geographical d...
 
Biophysical Characterization of I2-Thalassemic Red Blood Cells
submitted by jiffhatjins 2 years and 5 months ago
Thalassemia is the world's most common hereditary disease; therefore, more interest has been devoted for the development of the screening procedure of this disease. In I2-thalassemia major, the subject of the current study, impaired biosynthesis of beta-globin leads to accumulation of unpaired al...
 
Estimation of evapotranspiration with drainage lysimeters in the Taihang Mountain area, China
submitted by skaalva 2 years and 5 months ago
In this research, the evapotranspiration (ET) of three native vegetation communities were measured using drainage lysimeters in the Taihang Mountain area, China. They are a local grass, Themeda japonica, a local shrub, Vitex negundo var. heterophylla Rehd. and a mixture of both communities. The E...