This in vitro study evaluated the effects of nano-hydroxyapatite (n-HAp) toothpastes on remineralization of bovine enamel and dentin subsurface lesions.   : Specimens were demineralized, randomly divided into five groups, and exposed to an aqueous remineralizing solution for two and five weeks (37°C). Brushing procedures were performed with the respective toothpaste/storage solution slurry twice daily (2×5s; total contact time of the slurries 2×12s/d): storage in remineralizing solution only (); additional brushing with B (2 wt% zinc carbonate nano-hydroxyapatite, ZnCO3/n-HAp); BS (24 wt% ZnCO3/n-HAp); E (.14 wt% amine fluoride); or A (7 wt% pure n-HAp). Differences in mineral loss (ΔΔZ) before and.
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