This article is about heroines. It is concerned with the virtues of goodness, honesty, integrity and morality: nowadays reduced to values which are much praised in rhetoric but perhaps less observable in everyday life. Understood in this way, virtue has come to be regarded as a Victorian legacy. In The De-moralisation of Society: From Victorian Virtues to Modern Values (1996), the historian Gertrude Himmelfarb characterizes the Victorians as moralists who believed in virtues as qualities of character and morality that they regarded as necessary in a civilized society. She takes the view that virtures have been replaced by values that are relative and subjective. Any and all positions, desires and demands then become personal preferences that can be and are accommodated and met. The stories of the heroines of fifty years ago and more are stories of heroic virtue: of opposition. We are deceived when we are told they are stories of female oppression. Where, at this distance in time from these stories, we feel uncomfortable is with our own persuasive narratives of liberation and heterogeneity.
B-type natriuretic peptide (BNP) is a regulatory autacoid in the mammalian myocardium, whose functions play significant roles in health and disease. Previous work has identified that BNP protect myocardium through mitochondrial pathway-dependent mechanism against ischemia-reperfusion (I/R) injury...
Cystic Fibrosis (CF) is an inherited, multisystem disease characterised by defective salt and water transport across the secretory epithelia of the respiratory and gastrointestinal tracts. Much of the morbidity and mortality in CF results from inflammation and infection of the airways. However, s...
Thrombotic thrombocytopenic purpura (TTP) is a disorder with characteristic von Willebrand factor (VWF)-rich microthrombi affecting the arterioles and capillaries of multiple organs. The disorder frequently leads to early death unless the patients are treated with plasma exchange or infusion. Stu...
Chronic suppurative otitis media (CSOM) is one of the commonest disease entities encountered in otolaryngology practice. Due to poor economic conditions poor hygiene lack of education and death of knowledge about the disease and its complications, we frequently encounter patients of CSOM with ext...
Dialysis treatment prior to transplantation may contribute to premature mortality and graft loss in kidney-transplanted patients. In this prevalent cohort study (TransQol-HU Study), we analyzed the association between pre-transplant dialysis duration versus mortality and death-censored graft loss...
In order to study the anticancer effects and cellular apoptosis pathways induced by daidzein.Materials and methods: We used the human MCF-7 breast cancer cell line as a model and examined the apoptosis by Hoechst–propidium iodide staining fluorescence imaging and flow cytometry. Our data in...
Interstitial lung disease is a frequent complication of systemic sclerosis and currently is the leading cause of death. Our ability to predict which individuals are at greatest risk of developing clinically significant, progressive interstitial lung disease remains inadequate. Identification of c...
Colorectal cancer is the second most common cause of cancer-related death in the Western world. Its development is typically through colorectal adenomas. Colorectal cancer prevalence may be reduced substantially by primary prevention including colonoscopy and polypectomy. Secondary prevention app...
The epidemiology of cardiovascular disease in the black population of the Caribbean is important as attempts are made to understand the reasons for racial disparities in health outcomes in developed countries. Over the past 50 years, the Afro-Caribbean population (ie, Caribbean people of African ...
Extracellular adenosine disrupted mitochondrial membrane potentials in HuH-7 cells, a Fas-deficient human hepatoma cell line, and the effect was inhibited by the adenosine transporter inhibitor dipyridamole or by overexpressing Bcl-XL. Adenosine downregulated the expression of mRNAs and proteins ...
