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Gender influences the relationship between lung function and cardiac remodeling in hypertensive subjects
Hypertensive patients are predisposed to left ventricular (LV) remodeling and frequently exhibit decline in lung function as compared with the general population. Here, we investigated the association between spirometric and echocardiographic data in non-smoking hypertensive subjects and the role of gender in this regard. In a cross-sectional study, 107 hypertensive patients (60 women) enrolled...


Renal tubulointerstitial damage and salt-sensitive hypertension in chronic kidney disease: is the tubulointerstitium relevant beyond the glomerulus?
Excessive salt intake is a classic and common risk factor that scritically impacts hypertension and cardiovascular disease (CVD) outcome. Recent work has made us aware of the significance of excessive salt intake at the level of global health care. Salt dependency in hypertension is generally characterized by nocturnal hypertension.
Safety and clinical outcome in combination therapy for high-risk elderly hypertensive patients
To achieve the optimal target blood pressure level (<140/90 mm Hg) for the prevention of cardiovascular events, various combinations of antihypertensive drugs are often required.1 Meta-analysis demonstrated that the blood pressure reduction effects of different categories of drugs were additive and adverse symptoms attributable to thiazide diuretics, β-blocker...


Significance of serum Zn-α2-glycoprotein for the regulation of blood pressure
Zn-α2-glycoprotein (ZAG) (molecular weight=41 kDa) is one component in the α2 fraction of human plasma, and is reported to be associated with several diseases, such as cancers and metabolic syndromes. ZAG is also considered to be an important modulator of lipid metabolism. However, little is known about the correlation of serum ZAG levels with indicators of metabo...
Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability
Gomisin J (GJ) is a small molecular weight lignan found in Schisandra chinensis and has been demonstrated to have vasodilatory activity. In this study, the authors investigated the effect of GJ on blood pressure (BP) in angiotensin II (Ang II)-induced hypertensive mice. In addition, we determined the relative potencies of gomisin A (GA) and GJ with respect to vasodilatory activity and antihyper...


13-Oxo-9( Z ),11( E ),15( Z )-octadecatrienoic Acid Activates Peroxisome Proliferator-Activated Receptor γ in Adipocytes
Peroxisome proliferator-activated receptor (PPAR)γ is expressed in adipose tissue and plays a key role in the regulation of adipogenesis. PPARγ activators are known to have potent antihyperglycemic activity and are used to treat insulin resistance associated with diabetes. Therefore, many natural and synthetic agonists of PPARγ are used in the treatment of glucose disorders. In the present s...
Ionic Liquids Increase the Catalytic Efficiency of a Lipase (Lip1) From an Antarctic Thermophilic Bacterium
Lipases catalyze the hydrolysis and synthesis of triglycerides and their reactions are widely used in industry. The use of ionic liquids has been explored in order to improve their catalytic properties. However, the effect of these compounds on kinetic parameters of lipases has been poorly understood. A study of the kinetic parameters of Lip1, the most thermostable lipase from the supernatant o...

Pharmacokinetics of streptomycin sulfate in Staphylococcus aureus-infected Clarias gariepinus (Burchell 1822)
Most bacteria causing fish diseases in Nigeria have been observed to be susceptible to aminoglycosides like streptomycin. However, route of administration for effective therapy has been a challenge due to the reported poor intestinal absorption, hence a need to study its kinetics. Clarias gariepinus were divided into four groups of 14 fish each. Fish in A were Staphylococcus aureus-infected whi...
Evaluation of surface water quality and heavy metal indices of Ismailia Canal, Nile River, Egypt
Ismailia Canal is one of the most important branches of the Nile River in Egypt. It is the main source of drinking and irrigation water for many cities. Weighted arithmetic method of water quality index (WQI) was used to evaluate the water quality of Ismailia Canal according to drinking, irrigation and aquatic life water utilizations. The objective of the index is to transform complex water qua...

Analyzing how travelers choose scenic routes using route choice models
Finding a scenic route between two locations is a common trip planning task, in particular for tourists and recreational travelers. For the automated computation of a scenic route in a trip planning system it is necessary to identify which attributes of a route and its surroundings are associated with attractive scenery. This study uses a route choice model, more specifically a Path Size Logit ...
Effect of acetylation on the physico-chemical properties of Indian Horse Chestnut (Aesculus indica L.) starch
The present work was carried out to study the effect of acetylation (0, 3, 6 and 9 g vinyl acetate/gram starch) on the physico-chemical properties of starch, isolated from Indian horse chestnut (Aesculus indica). Work on starch acetylation and characterization from Indian horse chestnut has not been reported so far in literature. Moisture, protein, fat and ash content of native starch was found...

National—ethnic narratives in eleventh-century literary representations of Cnut
This article takes literary representations of Cnut, the Danish conqueror of England, as a case study of the construction of English identity in the eleventh century. It traces representations of Cnut in four literary texts composed over the course of the century: the Anglo-Saxon Chronicle, the Knútsdrápur, the Encomium Emmae Reginae, and Osbern of Canterbury's Translatio Sancti Æ...
The audience for Old English texts: Ælfric, rhetoric and ‘the edification of the simple’
There is a persistent view that Old English texts were mostly written to be read or heard by people with no knowledge of Latin, or little understanding of it, especially the laity. This is not surprising because it is what the texts themselves tend to say. In this article I argue that these statements about audience reflect two rhetorical devices and should not be understood literally. This has...
The sevenfold-fivefold-threefold litany of the saints in the Leofric Missal and beyond
The brief litany of saints in the Leofric Missal is the oldest complete extant specimen of the sevenfold-fivefold-threefold prayer used for baptism on Holy Saturday. This continental innovation became widespread in Anglo-Saxon England, and was used in Ireland into the twelfth century. The petitions of this special form, probably from an English source, appear in the brief litany of the Corpus I...
Constructing the monstrous body in Beowulf
The monstrosity of Grendel and his mother have long held the interest of Beowulf-scholars. Examining the bodily attributes of both figures in order to detect inter-textual patterns of diction, this article focuses on depictions of the monsters' skin, hands and blood. In analysing these attributes, it becomes clear that the Beowulf-poet's chosen descriptors align the monstrous body with manmade ...