RSS feed 

View All

Protein 4.1R attenuates autoreactivity in experimental autoimmune encephalomyelitis by suppressing CD4+ T cell activation
Immune synapse components contribute to multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) pathogenesis as they play important role in autoreative T cell activation. Protein 4.1R, a red cell membrane cytoskeletal protein, recently was identified as an important component of immunological synapse (IS) and acted as the negative regulator of CD4+ T cell activation. However...


Leishmaniasis and autoimmune diseases in pediatric age
Leishmaniasis is a group of diseases caused by the protozoa Leishmania, endemic in the Mediterranean countries. Clinical manifestations can be divided into three different forms: cutaneous leishmaniasis, mucosal leishmaniasis and the visceral leishmaniasis, the most severe form which is potentially lethal if untreated. Immunology and pathogenesis are complex: many different aspects of immune re...
Augmented screws in angular stable plating of the proximal humerus: What to do when revision is needed?
Bone cement augmentation of modified cannulated locking screws shows biomechanically and clinically good results for osteoporotic fracture management. Nevertheless, complications need to be considered and therefore implant removal should be tested for feasibility. Implant removal was simulated in 7 pairs of osteoporotic cadaveric humeri: During screw removal from an angular stable proximal hume...


In Vivo Analysis of Trapeziometacarpal Joint Arthrokinematics during Multi-directional Thumb Motions
The investigation of the joint arthrokinematics of the trapeziometacarpal joint is critical to comprehend the causative mechanism underlying this common form of osteoarthritis. Therefore, the purpose of this study is to evaluate the arthrokinematics of the trapeziometacarpal joint during thumb postures in vivo. Fifteen healthy participants were enrolled in this study. Static computed tomography...
Management of Acute Calcific Tendinitis Around the Hip Joint
Although the natural history of calcific tendinitis within the rotator cuff of the shoulder is established, the natural history of calcific tendinitis around the hip joint remains unknown. To examine the duration of symptoms including pain, the location of calcific tendinitis around the hip joint, the radiologic course of calcium phosphate crystals, and the proportion of patients who required s...


Lumbopelvic Control and Days Missed Because of Injury in Professional Baseball Pitchers
Recently, lumbopelvic control has been linked to pitching performance, kinematics, and loading; however, poor lumbopelvic control has not been prospectively investigated as a risk factor for injuries in baseball pitchers. Pitchers with poor lumbopelvic control during spring training are more likely to miss ≥30 days because of an injury through an entire baseball season than pitchers with goo...
Floating on Oil
We demonstrate that disk-shaped steel meshes coated with a superamphiphobic layer are able to float on water and on organic liquids. A coated disk-shaped steel mesh of 1 cm radius has a loading capacity of 17 mN in water and still remarkable 9 mN in n-hexadecane. Experimentally measured supporting forces and loading capacities agree well with theoretical predictions. Inspired by the giant water...

Folate Ligand Anchored Liquid Crystal Microdroplets Emulsion for in Vitro Detection of KB Cancer Cells
A kb cancer cell-selective, liquid crystal microdroplets emulsion is prepared using folic acid-conjugated block copolymers (PS-b-PAA-FA) and sodium dodecyl sulfate (SDS) as a mediator to induce configurational transitions in 4-cyano-4′-pentylbiphenyl (5CB) liquid crystal microdroplets emulsion. The prepared liquid crystal microdroplets emulsion has shown a configurational transition from radi...
Nanoscale Wetting and Fouling Resistance of Functionalized Surfaces: A Computational Approach
A computational modeling methodology has been developed and employed to characterize the nanoscale wettability and antifouling properties of functionalized hard and deformable surfaces, with a specific focus on poly(ethylene glycol) grafted substrates and their resistance to graphitic carbons. Empirical evidence suggests that the antifouling behavior of polyethylene PEG is associated with two m...

Topical petrolatum gel alone versus topical silver sulfadiazine with standard gauze dressings for the treatment of superficial partial thickness burns in adults: A randomized controlled trial
Non-extensive superficial partial thickness burns constitute a major proportion of burns. Conventional treatment involves regular changing of absorptive dressings including the application of a topical antimicrobial, commonly silver sulfadiazine. A systematic review has found insufficient evidence to support or refute such antimicrobial prophylaxis. Another review compared silver sulfadiazine d...
Talent Recruitment and Firm Performance: The Business of Major League Sports
Firms rely heavily on their investments in human capital to achieve profits. This research takes advantage of detailed information on worker performance and confidential information on firm revenue and operating costs to investigate the relationship between talent migration and firm profitability in major league sports, one of the few industries in which detailed information about the past perf...

Data Formats for Elementary Gas Phase Kinetics, Part 1: Unique Representations of Species at the Molecular Level
Standardized electronic formats for data are needed to efficiently and transparently communicate the results of scientific studies. A format for the unique identification of chemical species is a requirement in the field of chemistry, and the IUPAC International Chemical Identifier (InChI) has been widely adopted for this purpose. The InChI identifier has proved to be very useful. The InChI ide...
Progress in Understanding Low-Temperature Organic Compound Oxidation Using a Jet-Stirred Reactor
The jet-stirred reactor (JSR) has become a tool frequently used to study the oxidation of a wide range of reactants and particularly to obtain data for testing detailed kinetic models. This paper aims to discuss recent knowledge pertaining to low-temperature oxidation of hydrocarbons and oxygenated reactants that has been gained from using a JSR in connection with gas chromatography, especially...
Electron Transfer Reactions of Photochemically Generated Ruthenium(III)–Polypyridyl Complexes with Methionines
The oxidation of methionine (Met) plays an important role during biological conditions of oxidative stress as well as for protein stability. Ruthenium(III)–polypyridyl complexes, [Ru(NN)3]3+, generated from the photochemical oxidation of the corresponding Ru(II) complexes with molecular oxygen, undergo a facile electron transfer reaction with Met to form methionine sulfoxide (MetO) as the fin...
On the Application of the Pseudophase Model to Excited State Processes: Quenching of Pyrene by the Iodide Ion in β-Cyclodextrin and Micellar (SDS) Solutions
The pseudophase model, a two-state model, is based on the assumption of the existence of an equilibrium between these two states (free and bound), which is not perturbed in the case of a reactive event. This implies that the processes in which these two states participate must be slow, in relation to the exchange processes between these states. This condition does not hold in the case of very r...