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Methane and nitrous oxide analyzer comparison and emissions from dairy freestall barns with manure flushing and scraping
Continuous methane (CH4) and nitrous oxide (N2O) emission measurements were conducted at two crossflow-ventilated dairy freestall barns located in the state of Wisconsin, USA during a 19-month period from 2008 to 2010. The two cross-flow mechanically ventilated buildings (275 and 375 cow capacities) were evaluated in the National Air Emissions Monitoring Study. In September of 2008, the barns' ...


Prediction of high concentrations and concentration distribution of a continuous point source release in a semi-idealized urban canopy using CFD-RANS modeling
One of the key issues in recent research on dispersion in complex urban areas is the ability predicting high concentrations and concentration distribution of a pollutant released continuously from a point source. The present work addresses the question whether the CFD-RANS methodology can provide valid predictions of concentration peaks and distributions. A probabilistic and a deterministic app...
Influence of springtime biomass burning in South Asia on regional ozone (O3): A model based case study
In this study, for the first time, the influence of springtime (MAM) biomass burning in South Asia on regional ozone (O3) distribution has been evaluated using a regional chemical transport model (WRF-Chem) and the Fire Inventory from NCAR (FINNv1). Model results are compared with satellite retrievals of tropospheric column amounts of carbon monoxide (CO) from MOPI and nitrogen dioxide (NO2) fr...


Standardization of medium composition and agricultural waste in the production of p -hydroxybenzoic acid by Paecilomyces variotii
Biotransformation of p-coumaric acid by Paecilomyces variotii resulted in the accumulation of a metabolite which was identified as p-hydroxybenzoic acid. We studied the possibility of enhancing this metabolite by various parameters such as varying the concentration of substrate, addition of different nitrogen sources and carbon sources at varying concentration and use of different agricultural ...
Anthropophile elements in river sediments: Overview from the Seine River, France
In contrast to larger river systems that drain relatively pristine basins, little is known about the sediment geochemistry of rivers impacted by intense human activities. In this paper, we present a systematic investigation of the anthropogenic overprints on element geochemistry in sediments of the human-impacted Seine River, France. Most elements are fractionated by grain size, as shown by the...


Understanding a submarine eruption through time series hydrothermal plume sampling of dissolved and particulate constituents: West Mata, 2008–2012
Four cruises between 2008 and 2012 monitored the continuing eruption of West Mata volcano in the NE Lau Basin as it produced plumes of chemically altered water above its summit. Although large enrichments in 3He, CO2, Fe, and Mn were observed in the plumes, the most notable enrichment was that of H2, which reached concentrations as high as 14843 nM. Strongly enriched H2 concentrations in the wa...
The flow structure of jets from transient sources and implications for modeling short-duration explosive volcanic eruptions
We used laboratory experiments to examine the rise process in neutrally-buoyant jets that resulted from an unsteady supply of momentum, a condition that defines plumes from discrete Vulcanian- and Strombolian-style eruptions. We simultaneously measured the analog-jet discharge rate (the supply rate of momentum) and the analog-jet internal velocity distribution (a consequence of momentum transpo...

Understanding which parameters control shallow ascent of silicic effusive magma
The estimation of the magma ascent rate is key to predicting volcanic activity and relies on the understanding of how strongly the ascent rate is controlled by different magmatic parameters. Linking potential changes of such parameters to monitoring data is an essential step to be able to use these data as a predictive tool. We present the results of a suite of conduit flow models Soufrière th...
Imaging of CO2 bubble plumes above an erupting submarine volcano, NW Rota-1, Mariana Arc
NW Rota-1 is a submarine volcano in the Mariana volcanic arc located ~100 km north of Guam. Underwater explosive eruptions driven by magmatic gases were first witnessed there in 2004 and continued until at least 2010. During a March 2010 expedition, visual observations documented continuous but variable eruptive activity at multiple vents at ~560 m depth. Some vents released CO2 bubbles passive...

Influence of late Pleistocene glaciations on the hydrogeology of the continental shelf offshore Massachusetts, USA
Multiple late Pleistocene glaciations that extended onto the continental shelf offshore Massachusetts, USA may have emplaced as much as 100 km3 of freshwater (salinity less than 5 ppt) in continental shelf sediments. To estimate the volume and extent of offshore freshwater, we developed a three-dimensional, variable-density model that couples fluid flow and heat and solute transport for the con...
Die Versorgung mit mineralischen Rohstoffen – Entwicklungen auf internationaler und nationaler Ebene
Mineralische Rohstoffe sind von grundlegender Bedeutung für die europäische Wirtschaft. Sie sind für die Aufrechterhaltung und Verbesserung unserer Lebensqualität unentbehrlich. Der enorme Rohstoffbedarf fernöstlicher Wirtschaftsräume, in Kombination mit protektionistischen Maßnahmen einiger Länder, die einen fairen und freien Handel mit Rohstoffen einschränken, sowie raumordnerische u...

Alpha-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics
Hematopoietic cell transplantation is curative in many patients. However, graft-versus-host disease (GVHD), triggered by alloreactive donor cells, has remained a major complication. Here, we show an inverse correlation between plasma α-1-antitrypsin (AAT) levels in human donors and the development of acute GVHD in the recipients (n = 111; P = .0006). In murine models, treatment of transpl...
Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England
Impact on the timing of first postpartum venous thromboembolism (VTE) for women with specific risk factors is of crucial importance when planning the duration of thromboprophylaxis regimen. We observed this using a large linked primary and secondary care database containing 222 334 pregnancies resulting in live and stillbirth births between 1997 and 2010. We assessed the impact of risk factors ...
Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD)
Mutations in genes encoding proteins that are involved in mitochondrial heme synthesis, iron-sulfur cluster biogenesis, and mitochondrial protein synthesis have previously been implicated in the pathogenesis of the congenital sideroblastic anemias (CSAs). We recently described a syndromic form of CSA associated with B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD). Here ...
Splenic TFH expansion participates in B-cell differentiation and antiplatelet-antibody production during immune thrombocytopenia
Antiplatelet-antibody-producing B cells play a key role in immune thrombocytopenia (ITP) pathogenesis; however, little is known about T-cell dysregulations that support B-cell differentiation. During the past decade, T follicular helper cells (TFHs) have been characterized as the main T-cell subset within secondary lymphoid organs that promotes B-cell differentiation leading to antibody class-s...